Biomaterial Database

A case with nocturnal paroxysmal unilateral dystonia and interictal right frontal epileptic EEG focus: a lateralized variant of nocturnal paroxysmal dystonia? 1992

M Oguni, and H Oguni, and M Kozasa, and Y Fukuyama

Department of Pediatrics, Tokyo Women's Medical College, Japan.

We report here a patient with frequent nocturnal attacks, characterized by paroxysmal dystonic posturing of the left arm and contraction of the lower face, lasting 20-30 seconds. The attacks occurred in clusters of up to 20 spasms during the NREM stage of sleep. Interictal EEG showed clear-cut epileptic discharges in the right frontal region. Repeated ictal video-EEG recordings revealed only arousal pattern immediately before and during seizures except in those which evolved to left sided clonic hemiconvulsions. The dystonic attacks here described share many features of nocturnal paroxysmal dystonia (NPD) of Lugaresi and Cirignotta in common, including nocturnal periodic occurrence, absence of ictal EEG changes during attacks, and favorable response to CBZ, except for their unilateral nature. It was assumed that our case may be a lateralized variant of NPD and would further support the hypothesis that NPD is one particular form of frontal lobe epilepsy.

UI	MeSH Term	Description	Entries
D007839	Functional Laterality	Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.	Ambidexterity,Behavioral Laterality,Handedness,Laterality of Motor Control,Mirror Writing,Laterality, Behavioral,Laterality, Functional,Mirror Writings,Motor Control Laterality,Writing, Mirror,Writings, Mirror
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D004421	Dystonia	An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)	Muscle Dystonia,Dystonia, Diurnal,Dystonia, Limb,Dystonia, Paroxysmal,Diurnal Dystonia,Dystonia, Muscle,Limb Dystonia,Paroxysmal Dystonia
D004569	Electroencephalography	Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.	EEG,Electroencephalogram,Electroencephalograms
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012890	Sleep	A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.	Sleep Habits,Sleeping Habit,Sleeping Habits,Habit, Sleep,Habit, Sleeping,Habits, Sleep,Habits, Sleeping,Sleep Habit
D017034	Epilepsy, Frontal Lobe	A localization-related (focal) form of epilepsy characterized by seizures which arise in the FRONTAL LOBE.	Frontal Epilepsy, Benign, Childhood,Frontal Lobe Epilepsy,Benign Frontal Childhood Epilepsy,Childhood Benign Frontal Epilepsy,Epilepsy, Anterior Fronto-Polar,Epilepsy, Benign Frontal, Childhood,Epilepsy, Cingulate,Epilepsy, Opercular,Epilepsy, Orbito-Frontal,Epilepsy, Supplementary Motor,Anterior Fronto-Polar Epilepsies,Anterior Fronto-Polar Epilepsy,Cingulate Epilepsies,Cingulate Epilepsy,Epilepsies, Anterior Fronto-Polar,Epilepsies, Cingulate,Epilepsies, Orbito-Frontal,Epilepsies, Supplementary Motor,Epilepsy, Anterior Fronto Polar,Epilepsy, Orbito Frontal,Frontal Lobe Epilepsies,Opercular Epilepsies,Opercular Epilepsy,Orbito-Frontal Epilepsies,Orbito-Frontal Epilepsy,Supplementary Motor Epilepsies,Supplementary Motor Epilepsy