Late results following coronary artery bypass grafting. 1992

H J Dargie
Department of Cardiology, Western Infirmary, Glasgow, U.K.

Coronary bypass surgery is well into its third decade. The randomized trials of saphenous vein grafting together with the various registries[57-60] have provided us with a wealth of information not only on the effects of surgery but also on the natural history of coronary heart disease itself. Numerous improvements have been introduced, the most notable being the use of the IMA as an arterial conduit. Thus the results of the randomized trials which significantly influence our clinical decisions may not accurately reflect what modern surgery can now offer, especially to the type of patient being operated upon in the 1970s. Nevertheless the decision about whom to operate on probably will not change, at least in terms of clinical variables affected by the coronary anatomy and left ventricular function. But there is every expectation that the long-term clinical results of surgery will be better since graft patency has already been shown to have improved as a result of anti-platelet therapy and, most of all, by the IMA. We will never have a randomized trial to prove this, but experience to date justifies this conclusion. The other great change that has occurred during the last decade is angioplasty and hopefully the randomized trials will put this technique in perspective. But practice has already changed and surgery for single vessel disease is now much less commonly performed given the greater appreciation of the good prognosis with which this lesion is associated and the ease with which angioplasty can alleviate the symptoms it causes.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D002568 Certification Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty. Certification Level,Certification Levels,Certifications,Level, Certification,Levels, Certification
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000337 Aerospace Medicine That branch of medicine dealing with the studies and effects of flight through the atmosphere or in space upon the human body and with the prevention or cure of physiological or psychological malfunctions arising from these effects. (from NASA Thesaurus) Aviation Medicine,Space Medicine,Medicine, Aerospace,Medicine, Aviation,Medicine, Space
D001026 Coronary Artery Bypass Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion. Aortocoronary Bypass,Bypass, Coronary Artery,Bypass Surgery, Coronary Artery,Coronary Artery Bypass Grafting,Coronary Artery Bypass Surgery,Aortocoronary Bypasses,Artery Bypass, Coronary,Artery Bypasses, Coronary,Bypass, Aortocoronary,Bypasses, Aortocoronary,Bypasses, Coronary Artery,Coronary Artery Bypasses
D001359 Aviation Design, development, manufacture, and operation of heavier-than-air AIRCRAFT. Parachuting,Air Traffic Control,Control, Air Traffic,Traffic Control, Air
D015996 Survival Rate The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods. Cumulative Survival Rate,Mean Survival Time,Cumulative Survival Rates,Mean Survival Times,Rate, Cumulative Survival,Rate, Survival,Rates, Cumulative Survival,Rates, Survival,Survival Rate, Cumulative,Survival Rates,Survival Rates, Cumulative,Survival Time, Mean,Survival Times, Mean,Time, Mean Survival,Times, Mean Survival

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