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Injection of prodigiozan to mice 24 h before irradiation caused, by the time of the radiation effect, a decrease in the number of haemopoietic cells-precursors (CFUs and CFU-HM) in the bone marrow and an increase in the functional activity of stromal cell-precursors--the haemopoietic microenvironment of transfer units (HMTU); in the spleen, the number of CFUs decreased, but the number of CFU-HM increased considerably. During the postirradiation period, the haemopoietic and stromal precursors were damaged to a lesser extent, and CFUs, CFU-HM and HMTU recovered more readily in prodigiozan-protected animals than in unprotected mice; the HMTU restoration preceded the increase in CFUs and CFU-HM levels.
B B Moroz, and
V G Lebedev, and
O O Romashko, and
N A Levina
November 1984,
Biulleten' eksperimental'noi biologii i meditsiny,
B B Moroz, and
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N A Levina
January 1986,
International review of cytology,
B B Moroz, and
V G Lebedev, and
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January 1993,
Patologicheskaia fiziologiia i eksperimental'naia terapiia,
B B Moroz, and
V G Lebedev, and
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N A Levina
January 1991,
Radiobiologiia,
B B Moroz, and
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O O Romashko, and
N A Levina
January 2008,
Bulletin of experimental biology and medicine,
B B Moroz, and
V G Lebedev, and
O O Romashko, and
N A Levina
May 1990,
Experimental hematology,
B B Moroz, and
V G Lebedev, and
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N A Levina
November 2005,
Bulletin of experimental biology and medicine,
B B Moroz, and
V G Lebedev, and
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N A Levina
August 1985,
Transplantation,
B B Moroz, and
V G Lebedev, and
O O Romashko, and
N A Levina
January 1982,
Stem cells,
B B Moroz, and
V G Lebedev, and
O O Romashko, and
N A Levina
February 1987,
Radiation research,
