Biomaterial Database

The in vitro effect of Assafoetida on Trichomonas vaginalis. 2003

Nashwa I Ramadan, and Faisal M Al Khadrawy

Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.

Assafoetida is an oleo-gum resin obtained from the roots and stems of many Ferula species such as F. foetida Regel, F. asafoetida Linn, F. alliacea Boiss. and F. narthex Boiss, family Umbelliferae (carrot family), plants growing indigenously in Iran, Afghanistan and north of India. Assafoetida is commonly used as a flavoring agent in food and as a traditional medicine for many diseases in many parts of the world. In this work, the effect of Assafoetida on growth of Trichomonas vaginalis in vitro was studied and compared to metronidazole as a reference drug. It showed that Assafoetida had a potent antiparasitic effect on T. vaginalis compared to metronidazole, thus, worth further investigation to study its applicability in treatment of parasitic infections.

UI	MeSH Term	Description	Entries
D008517	Phytotherapy	Use of plants or herbs to treat diseases or to alleviate pain.	Herb Therapy,Herbal Therapy
D008795	Metronidazole	A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.	2-Methyl-5-nitroimidazole-1-ethanol,Bayer 5360,Clont,Danizol,Flagyl,Gineflavir,Metric,MetroGel,Metrodzhil,Metrogyl,Metronidazole Hydrochloride,Metronidazole Monohydrochloride,Metronidazole Phosphate,Metronidazole Phosphoester,Satric,Trichazol,Trichopol,Trivazol,Vagilen,2 Methyl 5 nitroimidazole 1 ethanol
D010938	Plant Oils	Oils derived from plants or plant products.	Oils, Plant,Oils, Vegetable,Plant Oil,Vegetable Oil,Vegetable Oils,Oil, Plant,Oil, Vegetable
D003374	Coumarins	Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid.	1,2-Benzopyrone Derivatives,1,2-Benzopyrones,Coumarin Derivative,Coumarine,1,2-Benzo-Pyrones,Benzopyran-2-ones,Coumarin Derivatives,Coumarines,1,2 Benzo Pyrones,1,2 Benzopyrone Derivatives,1,2 Benzopyrones,Benzopyran 2 ones,Derivative, Coumarin,Derivatives, 1,2-Benzopyrone,Derivatives, Coumarin
D005260	Female		Females
D005309	Ferula	A plant genus of the family APIACEAE. It contains pungent oils and resins. It is used to flavor curries, as a carminative, and as cat and dog repellent. The occasionally used common name of 'giant fennel' should not be confused with true fennel (FOENICULUM).	Asafoetida,Asa-foetida,Asafetida,Ferula foetida,Ferula harmonis,Ferula hermonis,Zallouh,Asa foetida,Asa-foetidas,Asafetidas,Asafoetidas,Ferula foetidas,Ferula harmoni,Ferula hermoni,Ferulas,Zallouhs,foetida, Ferula,harmonis, Ferula,hermonis, Ferula
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000981	Antiprotozoal Agents	Substances that are destructive to protozoans.	Schizonticides,Agents, Antiprotozoal
D012717	Sesquiterpenes	Fifteen-carbon compounds formed from three isoprenoid units with general formula C15H24.	Farnesanes,Farnesene,Farnesenes,Sesquiterpene,Sesquiterpene Derivatives,Sesquiterpenoid,Sesquiterpenoids,Derivatives, Sesquiterpene