-transparent.png){kind=logo}
PI-200 and PI-201, new platelet aggregation inhibitors produced by Streptomyces sp. A7498. Taxonomy, fermentation, isolation, physico-chemical properties, structure determination and biological properties. 1992
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
Research Center, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Two new platelet aggregation inhibitors, PI-200 and PI-201 were isolated from the fermentation broth of Streptomyces sp. A7498. PI-200 and PI-201 inhibited ADP-induced aggregation of rabbit platelets with an IC50 of 3.8 x 10(-4) M and 7.1 x 10(-4) M, respectively.
Related Publications
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
July 1989,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
December 1995,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
July 1994,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
May 1990,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
October 1994,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
March 1998,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
March 1999,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
December 1998,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
November 1994,
The Journal of antibiotics,
Y Kishimura, and
A Kawashima, and
T Kagamizono, and
M Yamagishi, and
K Matsumoto, and
Y Kawashima, and
K Hanada
August 2000,
The Journal of antibiotics,
