[Replacement of the thoracic aorta by sealed dacron prostheses (author's transl)]. 1978

R Akrami, and P Kalmar, and H Pokar, and V Tilsner

Dacron prostheses for replacement of the thoracic aorta were sealed with bioadhesive following the Viennese method. Native human fibrinogen was brought to coagulation by adding thrombin. Factor XIII was also added in order to accelerate polymerisation and to reinforce fibrin formation in the presence of thrombin and CaCl2, thus producing a stable thrombus. In order to avoid local fibrinolysis a fast but short-acting as well as a slow but longer-acting antifibrinolytic agent was added. This method was applied in twenty patients. The prostheses remained completely impermeable to blood after resuming circulation in spite of full heparinization. No post-operative haemorrhages from the prostheses were observed.

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D011093 Polyethylene Terephthalates Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics. Dacron,Nalophan,PET Polymer,Poly(Ethylene Terephtalate),Polyethylene Terephthalate,Tedlar,Dacrons,Nalophans,PET Polymers,Tedlars,Terephthalate, Polyethylene,Terephthalates, Polyethylene
D001807 Blood Vessel Prosthesis Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels. Vascular Prosthesis,Blood Vessel Prostheses,Tissue-Engineered Vascular Graft,Graft, Tissue-Engineered Vascular,Grafts, Tissue-Engineered Vascular,Prostheses, Blood Vessel,Prostheses, Vascular,Prosthesis, Blood Vessel,Prosthesis, Vascular,Tissue Engineered Vascular Graft,Tissue-Engineered Vascular Grafts,Vascular Graft, Tissue-Engineered,Vascular Grafts, Tissue-Engineered,Vascular Prostheses,Vessel Prostheses, Blood,Vessel Prosthesis, Blood
D005340 Fibrinogen Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001013 Aorta, Thoracic The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA. Aorta, Ascending,Aorta, Descending,Aortic Arch,Aortic Root,Arch of the Aorta,Descending Aorta,Sinotubular Junction,Ascending Aorta,Thoracic Aorta,Aortic Roots,Arch, Aortic,Ascending Aortas,Junction, Sinotubular,Root, Aortic,Sinotubular Junctions
D014014 Tissue Adhesives Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses. Adhesive, Tissue,Adhesives, Tissue,Tissue Adhesive

Related Publications

R Akrami, and P Kalmar, and H Pokar, and V Tilsner
October 1997, The Annals of thoracic surgery,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
December 1974, Thoraxchirurgie, vaskulare Chirurgie,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
January 1980, Journal de chirurgie,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
September 1957, Surgery, gynecology & obstetrics,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
January 1978, Chirurgie pediatrique,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
March 1995, Annals of vascular surgery,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
January 1982, Zentralblatt fur Chirurgie,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
September 1993, The Journal of thoracic and cardiovascular surgery,
R Akrami, and P Kalmar, and H Pokar, and V Tilsner
December 1972, Annals of surgery,
Copied contents to your clipboard!