-transparent.png){kind=logo}
An anti-inflammatory factor (AIF) was highly purified from normal bovine serum. The purified AIF was a polysaccharide which was formed from a low molecular substance Pro-AIF by macromolecularization. AIF showed potent inhibitory activities against carrageenin induced edema in rats and PMN-leucocyte chemotaxis. It showed no inhibition in cutaneous reaction with serotonin, bradykinin or a mediator releaser compound 48/80. No inhibition was also observed in thermally induced pain, reversed passive Arthus reaction and adjuvant polyarthritis in rats. With these results, the role of AIF in inflammation was discussed.
Related Publications
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
October 1995,
Biochimica et biophysica acta,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
January 1989,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
March 2017,
International journal of biological macromolecules,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
August 1982,
The Journal of biological chemistry,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
August 1981,
The Journal of biological chemistry,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
June 1982,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
January 2011,
Fish & shellfish immunology,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
March 1991,
Biochemistry,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
July 1987,
Experimental eye research,
E Misaka, and
K Matsuda, and
K Kobayashi, and
Y Endo, and
T Kojima, and
Y Iizuka
July 1984,
Journal of biochemistry,
