Biomaterial Database

Hypohalites and related oxidants as chemiluminescence reagents: a review. 2004

Paul S Francis, and Neil W Barnett, and Simon W Lewis, and Kieran F Lim

Centre for Chiral and Molecular Technologies, School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria 3217, Australia. psf@deakin.edu.au

This review concerns the use of hypochlorite, hypobromite and related oxidants (such as N-bromosuccinimide and 1,3-dibromo-5,5-dimethylhydantoin) as chemiluminescence reagents and includes references to 249 papers that were published prior to mid-2003. Particular emphasis has been placed on proposed emitting species and the mechanisms of the light-producing pathways. The analytical applications of this chemistry have been summarized in three tables: (1) quantification of hypohalites and related compounds (including halides, which are initially oxidized); (2) enhancement or inhibition of luminol chemiluminescence; and (3) direct chemiluminescence reactions with hypohalite reagents.

UI	MeSH Term	Description	Entries
D006997	Hypochlorous Acid	An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.	Hypochlorite,Hypochlorous Acids
D008163	Luminescent Measurements	Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.	Bioluminescence Measurements,Bioluminescent Assays,Bioluminescent Measurements,Chemiluminescence Measurements,Chemiluminescent Assays,Chemiluminescent Measurements,Chemoluminescence Measurements,Luminescence Measurements,Luminescent Assays,Luminescent Techniques,Phosphorescence Measurements,Phosphorescent Assays,Phosphorescent Measurements,Assay, Bioluminescent,Assay, Chemiluminescent,Assay, Luminescent,Assay, Phosphorescent,Assays, Bioluminescent,Assays, Chemiluminescent,Assays, Luminescent,Assays, Phosphorescent,Bioluminescence Measurement,Bioluminescent Assay,Bioluminescent Measurement,Chemiluminescence Measurement,Chemiluminescent Assay,Chemiluminescent Measurement,Chemoluminescence Measurement,Luminescence Measurement,Luminescent Assay,Luminescent Measurement,Luminescent Technique,Measurement, Bioluminescence,Measurement, Bioluminescent,Measurement, Chemiluminescence,Measurement, Chemiluminescent,Measurement, Chemoluminescence,Measurement, Luminescence,Measurement, Luminescent,Measurement, Phosphorescence,Measurement, Phosphorescent,Measurements, Bioluminescence,Measurements, Bioluminescent,Measurements, Chemiluminescence,Measurements, Chemiluminescent,Measurements, Chemoluminescence,Measurements, Luminescence,Measurements, Luminescent,Measurements, Phosphorescence,Measurements, Phosphorescent,Phosphorescence Measurement,Phosphorescent Assay,Phosphorescent Measurement,Technique, Luminescent,Techniques, Luminescent
D008165	Luminol	5-Amino-2,3-dihydro-1,4-phthalazinedione. Substance that emits light on oxidation. It is used in chemical determinations.
D010084	Oxidation-Reduction	A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).	Redox,Oxidation Reduction
D001959	Bromates	Negative ions or salts derived from bromic acid, HBrO3.	Bromate
D006219	Halogens	A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.	Halogen,Group 17 Elements,Elements, Group 17
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular
D016877	Oxidants	Electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION).	Oxidant,Oxidizing Agent,Oxidizing Agents,Agent, Oxidizing,Agents, Oxidizing
D017672	Nitrogen Compounds	Inorganic compounds that contain nitrogen as an integral part of the molecule.	Compounds, Nitrogen