The report contains the analysis results of 53 keratoplasty procedures in the treatment of patients with severe and extra severe burns of eyes (185 cases within 6 years). On the basis of the obtained results, the authors conclude that the active surgical approach, when used soon after trauma (necrectomy, autotenoplasty, bloody blepharorrhaphy), cut significantly the rate of indications for emergency keratoplasty (to 9% only in cases involving the presence of a deep defect caused by the thermal affection or the presence of burn-agent particles in the corneal stroma); an extra severe burn is the absolute indication for lamellar keratoplasty; indications for transplantation of the cornea, 1 week after trauma and more, arise, when there is ulceration (especially, perforation), due to a prolonged and ineffective therapy and due to an inadequate surgical tactics. The authors suggest the criteria for a substantiated and more effective use of transplantation of the cornea in the treatment of eye burns.