[Multiple phaeochomocytomas (author's transl)]. 1978

G Schindler, and R Hippéli, and F Longin

Multiple phaeochromocytomas represent a polytopic form of chromaffin tumours. The tumours may arise simultaneously or sequentially in chromaffin tissue, particularly in the retroperitoneal space. Malignancy can only be assumed if there are metastases to organs which do not contain chromaffin tissue. Their origin may be regarded as a dysontogenetic event. The clinical picture is dominated by the excretion of catecholamines. Laboratory tests are therefore used to determine the suspicion of the presence of a chromaffin tumour. A patient with an eight-year history is described, who had had four operations and in whom, by radiology or surgery, seven phaeochromocytomas had been found. The value of various radiological methods is discussed. The most informative method is arteriography; in view of the possibility of multiple tumours, aortography should be carried out in the first instance.

UI MeSH Term Description Entries
D008297 Male Males
D009378 Neoplasms, Multiple Primary Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites. Neoplasms, Synchronous,Neoplasms, Synchronous Multiple Primary,Multiple Primary Neoplasms,Multiple Primary Neoplasms, Synchronous,Synchronous Multiple Primary Neoplasms,Synchronous Neoplasms,Multiple Primary Neoplasm,Neoplasm, Multiple Primary,Neoplasm, Synchronous,Primary Neoplasm, Multiple,Primary Neoplasms, Multiple,Synchronous Neoplasm
D010673 Pheochromocytoma A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298) Pheochromocytoma, Extra-Adrenal,Extra-Adrenal Pheochromocytoma,Extra-Adrenal Pheochromocytomas,Pheochromocytoma, Extra Adrenal,Pheochromocytomas,Pheochromocytomas, Extra-Adrenal
D002395 Catecholamines A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE. Catecholamine,Sympathin,Sympathins
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000310 Adrenal Gland Neoplasms Tumors or cancer of the ADRENAL GLANDS. Adrenal Cancer,Adrenal Gland Cancer,Adrenal Neoplasm,Cancer of the Adrenal Gland,Neoplasms, Adrenal Gland,Adrenal Cancers,Adrenal Gland Cancers,Adrenal Gland Neoplasm,Adrenal Neoplasms,Cancer, Adrenal,Cancer, Adrenal Gland,Cancers, Adrenal,Cancers, Adrenal Gland,Neoplasm, Adrenal,Neoplasm, Adrenal Gland,Neoplasms, Adrenal
D000311 Adrenal Glands A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS. Adrenal Gland,Gland, Adrenal,Glands, Adrenal
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000792 Angiography Radiography of blood vessels after injection of a contrast medium. Arteriography,Angiogram,Angiograms,Angiographies,Arteriographies

Related Publications

G Schindler, and R Hippéli, and F Longin
March 1980, [Rinsho ketsueki] The Japanese journal of clinical hematology,
G Schindler, and R Hippéli, and F Longin
December 1977, Aichi Gakuin Daigaku Shigakkai shi,
G Schindler, and R Hippéli, and F Longin
October 1977, MMW, Munchener medizinische Wochenschrift,
G Schindler, and R Hippéli, and F Longin
January 1981, Polski przeglad radiologii i medycyny nuklearnej,
G Schindler, and R Hippéli, and F Longin
January 1981, Revue de stomatologie et de chirurgie maxillo-faciale,
G Schindler, and R Hippéli, and F Longin
April 1982, Ceskoslovenska dermatologie,
G Schindler, and R Hippéli, and F Longin
January 1981, La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
G Schindler, and R Hippéli, and F Longin
January 1979, Neuro-Chirurgie,
G Schindler, and R Hippéli, and F Longin
January 1978, Kyobu geka. The Japanese journal of thoracic surgery,
G Schindler, and R Hippéli, and F Longin
October 1978, Annales de chirurgie thoracique et cardio-vasculaire,
Copied contents to your clipboard!