Should all placentas be sent to pathology for examination after delivery room triage? A cohort of 88 placentas was prospectively obtained and examined from low-risk, singleton, term pregnancies after uneventful delivery. All patients had a normal prenatal testing and anatomy ultrasound. Fifty-one placentas (58%) were normal. Thirty-seven of the placental cohort (42%) had abnormal findings. Thirteen of the abnormal placentas (35.1%) showed pathology unassociated with fetal compromise. Twenty-four of the placentas (27.3% of the total cohort and 64.9% of the abnormal placentas) showed findings associated with fetal compromise. The most common pathologies were marginal cord insertion, chorioamnionitis, and abruption. Routine placental examination is not indicated, according to our data, in low-risk, singleton, and term pregnancy unless the placenta is determined to be abnormal at delivery examination.