Biomaterial Database

Occult hemophilia: prolonged bleeding follows extraction. 1992

J E Humphries, and R C Baker

Departments of Internal Medicine and Pathology, University of Virginia, Charlottesville 22908.

A 51-year-old man had delayed and recurrent bleeding after tooth extractions. Occult hemophilia B was discovered. This case emphasizes the importance of evaluating patients for an underlying coagulopathy when bleeding greater than expected occurs. In this case, the patient had no personal or family history of bleeding.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008437	Maxilla	One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.	Maxillae,Maxillary Bone,Bone, Maxillary,Bones, Maxillary,Maxillary Bones,Maxillas
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010314	Partial Thromboplastin Time	The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.	Activated Partial Thromboplastin Time,Cephalin-Kaolin Coagulation Time,Kaolin-Cephalin Coagulation Time,Thromboplastin Time, Partial,Coagulation Time, Cephalin-Kaolin,Cephalin Kaolin Coagulation Time,Coagulation Time, Cephalin Kaolin,Coagulation Time, Kaolin-Cephalin,Kaolin Cephalin Coagulation Time
D002836	Hemophilia B	A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)	Christmas Disease,Factor IX Deficiency,Deficiency, Factor IX,F9 Deficiency,Haemophilia B,Hemophilia B Leyden,Hemophilia B(M),Plasma Thromboplastin Component Deficiency,Bs, Hemophilia,Deficiencies, F9,Deficiencies, Factor IX,Deficiency, F9,Disease, Christmas,F9 Deficiencies,Factor IX Deficiencies,Haemophilia Bs,Hemophilia Bs,Hemophilia Bs (M)
D003730	Dental Care for Disabled	Dental care for the emotionally, mentally, or physically disabled patient. It does not include dental care for the chronically ill (	Dental Care for Handicapped,Dentistry for Disabled,Dentistry for Handicapped,Disabled, Dentistry for,Handicapped, Dentistry for
D006472	Oral Hemorrhage	Bleeding from the blood vessels of the mouth, which may occur as a result of injuries to the mouth, accidents in oral surgery, or diseases of the gums.	Hemorrhage, Oral,Oral Hemorrhages
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014081	Tooth Extraction	The surgical removal of a tooth. (Dorland, 28th ed)	Extraction, Tooth,Extractions, Tooth,Tooth Extractions
D016063	Blood Loss, Surgical	Loss of blood during a surgical procedure.	Hemorrhage, Surgical,Surgical Blood Loss,Surgical Hemorrhage,Surgical Blood Losses,Surgical Hemorrhages