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Aspirates of bone marrow with chronic lymphocytic leukemia, hairy cell leukemia, and Richter's syndrome were stained by the argyrophilic nucleolar organizer region (AgNOR) method and analyzed. The AgNOR configurations of small cells of chronic lymphocytic leukemia, hairy cell leukemia, and lymphosarcoma cells were similar and most often consisted of a single large dot, a single small regular bleb, and two dots of various sizes, similar to patterns of normal lymphocytes. The large cells of chronic lymphocytic leukemia and prolymphocytic leukemia cells transformed from chronic lymphocytic leukemia contained larger AgNORs (group II), that is patterns consistent with proliferation. Richter's syndrome lymphoma cells contained even larger AgNORs. A single large regular bleb, small regular bleb and large irregular bleb were most common. Cells with only small structures were very rare.
E P Nikicicz, and
D H Norback
January 1999,
Journal of veterinary internal medicine,
E P Nikicicz, and
D H Norback
January 2002,
Journal of hepato-biliary-pancreatic surgery,
E P Nikicicz, and
D H Norback
January 1992,
Nihon Geka Gakkai zasshi,
E P Nikicicz, and
D H Norback
January 1996,
Histology and histopathology,
E P Nikicicz, and
D H Norback
April 1992,
Zentralblatt fur Pathologie,
E P Nikicicz, and
D H Norback
August 1992,
Acta pathologica japonica,
E P Nikicicz, and
D H Norback
March 1994,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
E P Nikicicz, and
D H Norback
October 1997,
Japanese journal of clinical oncology,
E P Nikicicz, and
D H Norback
October 1995,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
E P Nikicicz, and
D H Norback
January 1995,
Hepato-gastroenterology,
