-transparent.png){kind=logo}
Cephalexin was structurally modified by the attachment of a spacer at the carboxylic acid through which it was subsequently covalently attached to BSA. This method permitted the molecule to be attached without cleavage of the beta-lactam ring giving a conjugate distinct from previously described immunogenic preparations of penicillins and cephalosporins. This approach required the development of a novel spacer molecule, and its synthesis and characterisation are reported. Rabbits were used to raise antisera and the antibodies produced were characterised with respect to their reactivity with cephalexin and various analogues, other cephalosporins, and a number of penicillins.
E H Kachab, and
W Y Wu, and
C B Chapman
March 1999,
Contemporary topics in laboratory animal science,
E H Kachab, and
W Y Wu, and
C B Chapman
January 1994,
Methods in molecular biology (Clifton, N.J.),
E H Kachab, and
W Y Wu, and
C B Chapman
December 1978,
Hospital practice,
E H Kachab, and
W Y Wu, and
C B Chapman
January 2017,
Methods in molecular biology (Clifton, N.J.),
E H Kachab, and
W Y Wu, and
C B Chapman
January 2022,
Methods in molecular biology (Clifton, N.J.),
E H Kachab, and
W Y Wu, and
C B Chapman
January 1976,
Bulletin of the World Health Organization,
E H Kachab, and
W Y Wu, and
C B Chapman
February 2010,
Clinical chemistry,
E H Kachab, and
W Y Wu, and
C B Chapman
May 1985,
Journal of steroid biochemistry,
E H Kachab, and
W Y Wu, and
C B Chapman
May 1985,
Journal of steroid biochemistry,
E H Kachab, and
W Y Wu, and
C B Chapman
January 1982,
Journal of biological standardization,
