Biomaterial Database

Peritoneal ultrafiltration after chronic exposure to dialysis fluid. 1992

N D Slater, and G H Cope, and A T Raftery

Renal and Transplant Unit, Northern General Hospital, Sheffield, U.K.

Eleven rats were given twice-daily intraperitoneal injections of 20 mL of dialysis fluid containing 4.5% glucose for 6 weeks. The peritoneal ultrafiltration capacity of this group was compared with that of a control group of 10 rats that had received no injections by measuring the volume and glucose concentration of the dialysate remaining in the peritoneal cavity 2 hours after injection. Animals that had received injections of dialysis fluid showed significant loss of peritoneal ultrafiltration: volume of dialysate remaining in the control group was 31 (13-35) mL, and in the experimental group was 25 (11-45) mL, with p less than 0.02 (Mann-Whitney). This was associated with enhanced glucose absorption: glucose absorbed by the control group was 382 (312-706) mg, and 595 (435-738) mg in the experimental group (p less than 0.002, Mann-Whitney).

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010537	Peritoneum	A membrane of squamous EPITHELIAL CELLS, the mesothelial cells, covered by apical MICROVILLI that allow rapid absorption of fluid and particles in the PERITONEAL CAVITY. The peritoneum is divided into parietal and visceral components. The parietal peritoneum covers the inside of the ABDOMINAL WALL. The visceral peritoneum covers the intraperitoneal organs. The double-layered peritoneum forms the MESENTERY that suspends these organs from the abdominal wall.	Parietal Peritoneum,Peritoneum, Parietal,Peritoneum, Visceral,Visceral Peritoneum,Parametrium,Parametriums
D011919	Rats, Inbred Strains	Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.	August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D005947	Glucose	A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.	Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014462	Ultrafiltration	The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).
D015314	Dialysis Solutions	Solutions prepared for exchange across a semipermeable membrane of solutes below a molecular size determined by the cutoff threshold of the membrane material.	Dialysate,Dialysis Solution,Dialyzate,Dialysates,Dialyzates,Solution, Dialysis,Solutions, Dialysis
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

N D Slater, and G H Cope, and A T Raftery

Peritoneal ultrafiltration and fluid reabsorption during peritoneal dialysis.

January 1989, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,

N D Slater, and G H Cope, and A T Raftery

Peritoneal ultrafiltration dialysis: enhanced urea transfer using hypertonic peritoneal dialysis fluid.

June 1966, The Journal of clinical investigation,

N D Slater, and G H Cope, and A T Raftery

Ultrafiltration by hyperosmotic peritoneal dialysis fluid excludes intracellular solutes.

January 1984, American journal of nephrology,

N D Slater, and G H Cope, and A T Raftery

Poor ultrafiltration shortly after peritoneal dialysis initiation.

December 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,

N D Slater, and G H Cope, and A T Raftery

Ultrafiltration capacity and peritoneal fluid kinetics in continuous ambulatory peritoneal dialysis patients.

January 2008, Artificial organs,

N D Slater, and G H Cope, and A T Raftery

Measurement of peritoneal fluid absorption and ultrafiltration during peritoneal dialysis using segmental bioimpedance.

July 2022, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference,

N D Slater, and G H Cope, and A T Raftery

Net ultrafiltration in peritoneal dialysis: role of direct fluid absorption into peritoneal tissue.

January 1992, Blood purification,

N D Slater, and G H Cope, and A T Raftery

[Peritoneal dialysis, ultrafiltration and hyperosmolarity].

August 1976, Schweizerische medizinische Wochenschrift,

N D Slater, and G H Cope, and A T Raftery

[Ultrafiltration characteristics of peritoneal dialysis].

March 1983, Vnitrni lekarstvi,

N D Slater, and G H Cope, and A T Raftery

Chronic exposure of mouse peritoneum to peritoneal dialysis fluid: structural and functional alterations of the peritoneal membrane.

January 2009, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,