-transparent.png){kind=logo}
Hydrophobic peptides were isolated from the phospholipid fraction of human bile, plasma and spleen by exclusion chromatography in organic solvents. From plasma, the activation peptide of C1 protease inhibitor was recovered, from spleen the activation peptide of alpha 1-antitrypsin, and from bile, both these peptides, as well as a fragment generated by proteolytic cleavage of alpha 1-antitrypsin six residues N-terminal of the P1-P1' peptide bond. Cleavages in this region inactivate antiproteases but have previously not been reported to occur in vivo. These peptides in human bile may reflect physiological actions in regulation of antiproteolytic activity or bile secretion processes, and/or be of importance for the physicochemical state of cholesterol, phospholipids and bile acids in bile.
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
January 1985,
Journal of medicine,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
February 1981,
Biochemical and biophysical research communications,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
January 1985,
Journal of medicine,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
January 1990,
Human heredity,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
September 2004,
Virus research,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
November 1991,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
March 1985,
Life sciences,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
January 1989,
Annales de biologie clinique,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
June 1977,
Canadian journal of biochemistry,
J Johansson, and
S Gröndal, and
J Sjövall, and
H Jörnvall, and
T Curstedt
August 1985,
Pediatric research,
