Biomaterial Database

[Microcirculation during inhalation of 100% oxygen in rabbits]. 1992

A Taguchi

Department of Anesthesiology, Tokyo Women's Medical College.

Using a rabbit ear chamber (REC), the author compared the effect of air inhalation and that of 100% oxygen inhalation on microcirculation of rabbits. Eight rabbits, weighing 3-4 kg, were used for this study. After observing the microcirculation under air inhalation, the inspired gas was changed to 100% oxygen and the microcirculation was again observed. This procedure was repeated twice to confirm any changes that had been observed. No significant changes were observed in the blood pressure, heart rate and pulse pressure by inhaling either O2 concentration. During the inhalation of 100% oxygen, the diameter, blood-flow velocity and blood-flow rate of the arterioles were markedly reduced (P less than 0.01). All these parameters observed in the venules during air inhalation showed no significant differences compared with the values taken during 100% oxygen inhalation. This study using REC has shown that inhalation of 100% oxygen causes microcirculatory changes especially affecting the arterioles.

UI	MeSH Term	Description	Entries
D008833	Microcirculation	The circulation of the BLOOD through the MICROVASCULAR NETWORK.	Microvascular Blood Flow,Microvascular Circulation,Blood Flow, Microvascular,Circulation, Microvascular,Flow, Microvascular Blood,Microvascular Blood Flows,Microvascular Circulations
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D000280	Administration, Inhalation	The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.	Drug Administration, Inhalation,Drug Administration, Respiratory,Drug Aerosol Therapy,Inhalation Drug Administration,Inhalation of Drugs,Respiratory Drug Administration,Aerosol Drug Therapy,Aerosol Therapy, Drug,Drug Therapy, Aerosol,Inhalation Administration,Administration, Inhalation Drug,Administration, Respiratory Drug,Therapy, Aerosol Drug,Therapy, Drug Aerosol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia