Biomaterial Database

Normal fetal Doppler inferior vena cava, transtricuspid, and umbilical artery flow velocity waveforms between 11 and 16 weeks' gestation. 1992

J W Wladimiroff, and T W Huisman, and P A Stewart, and T Stijnen

Department of Obstetrics and Gynecology, Academic Hospital Rotterdam-Dijkzigt, Erasmus University, The Netherlands.

OBJECTIVE Our objectives were to determine flow velocity waveform patterns in the fetal inferior vena cava and to relate these waveforms to transtricuspid and umbilical artery waveforms and fetal heart rate in early gestation. METHODS Doppler waveforms were recorded in 40 normal fetuses at 11 to 16 weeks of gestation. Only transvaginal scanning was carried out at 11 to 12 weeks and only transabdominal scanning was used at 15 to 16 weeks. RESULTS The ratio of time velocity integrals of flow from the inferior vena cava during systole and early diastole, the percentage of reverse flow in this vessel, the pulsatility index from the umbilical artery, and the fetal heart rate were negatively correlated with gestational age. Peak E-wave and A-wave velocities and E/A ratios from the transtricuspid waveforms were positively correlated with gestational age. CONCLUSIONS Early normal pregnancies are associated with remarkable changes in fetal flow velocity waveforms at both the cardiac and the extracardiac level.

UI	MeSH Term	Description	Entries
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001783	Blood Flow Velocity	A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.	Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D005260	Female		Females
D005333	Fetus	The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.	Fetal Structures,Fetal Tissue,Fetuses,Mummified Fetus,Retained Fetus,Fetal Structure,Fetal Tissues,Fetus, Mummified,Fetus, Retained,Structure, Fetal,Structures, Fetal,Tissue, Fetal,Tissues, Fetal
D005865	Gestational Age	The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated from the onset of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization. It is also estimated to begin from fertilization, estrus, coitus, or artificial insemination.	Embryologic Age,Fetal Maturity, Chronologic,Chronologic Fetal Maturity,Fetal Age,Maturity, Chronologic Fetal,Age, Embryologic,Age, Fetal,Age, Gestational,Ages, Embryologic,Ages, Fetal,Ages, Gestational,Embryologic Ages,Fetal Ages,Gestational Ages
D006340	Heart Rate, Fetal	The heart rate of the FETUS. The normal range at term is between 120 and 160 beats per minute.	Fetal Heart Rate,Fetal Heart Rates,Heart Rates, Fetal,Rate, Fetal Heart,Rates, Fetal Heart
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014261	Tricuspid Valve	The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.	Tricuspid Valves,Valve, Tricuspid,Valves, Tricuspid