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Red blood cells contain a protein that activates membrane-bound (Ca2+ + Mg2+)-ATPase and Ca2+ transport. The red blood cell activator protein is similar to a modulator protein that stimulates cyclic AMP phosphodiesterase. Wang and Desai [Journal of Biological Chemistry 252:4175--4184, 1977] described a modulator-binding protein that antagonizes the activation of cyclic AMP phosphodiesterase by modulator protein. In the present work, modulator-binding protein was shown to antagonize the activation of (Ca2+ + Mg2+)-ATPase and Ca2+ transport by red blood cell activator protein. The results further demonstrate the similarity between the activator protein from human red blood cells and the modulator protein from bovine brain.
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
January 1979,
American journal of hematology,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
September 1980,
Molecular pharmacology,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
January 1980,
American journal of hematology,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
August 1977,
Biochemical and biophysical research communications,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
November 1973,
Biochimica et biophysica acta,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
January 1984,
Biochimica et biophysica acta,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
March 1985,
Brain research,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
February 1981,
Biochimica et biophysica acta,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
January 1980,
Annals of the New York Academy of Sciences,
F L Larsen, and
B U Raess, and
T R Hinds, and
F F Vincenzi
December 1986,
Biochimica et biophysica acta,
