Primary headaches in children and adolescents. 2004

L Grazzi
Headache Centre, National Neurological Institute C. Besta, Via Celoria 11, I-20133 Milan, Italy. liciagrazzi@mac.com

Headache is one of the commonest conditions to affect children and adolescents in industrialised countries. Studies indicate a prevalence of 8-60%. In over 40% of migraineurs the condition begins before 18 years of age. For clinical researchers, headache in the young is of interest because its causes are easier to investigate than in older people, as the clinical history is brief, the condition has had no time to become chronic, and it is not accompanied by changes in pain neuromodulation and neurotransmission, or the development of a chronic pain/stress-related personality that is common in adults with longstanding headache. The wide variation in reported headache prevalence in young people may be ascribed to lack of representativity of studies and vagueness of diagnostic criteria in studies performed before 1988. The publication of the International Headache Society IHS classification in 1988 for the first time made it possible to accurately diagnose the various headache forms. The diagnostic criteria for adults were adopted for use in young patients. Since that time a burgeoning number of studies on headache in young people have been published.

UI MeSH Term Description Entries
D008881 Migraine Disorders A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) Acute Confusional Migraine,Headache, Migraine,Status Migrainosus,Abdominal Migraine,Cervical Migraine Syndrome,Hemicrania Migraine,Migraine,Migraine Headache,Migraine Variant,Sick Headache,Abdominal Migraines,Acute Confusional Migraines,Cervical Migraine Syndromes,Disorder, Migraine,Disorders, Migraine,Headache, Sick,Headaches, Migraine,Headaches, Sick,Hemicrania Migraines,Migraine Disorder,Migraine Headaches,Migraine Syndrome, Cervical,Migraine Syndromes, Cervical,Migraine Variants,Migraine, Abdominal,Migraine, Acute Confusional,Migraine, Hemicrania,Migraines,Migraines, Abdominal,Migraines, Acute Confusional,Migraines, Hemicrania,Sick Headaches,Variant, Migraine,Variants, Migraine
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000639 Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. Amineurin,Amitrip,Amitriptylin Beta,Amitriptylin Desitin,Amitriptylin RPh,Amitriptylin-Neuraxpharm,Amitriptyline Hydrochloride,Amitrol,Anapsique,Apo-Amitriptyline,Damilen,Domical,Elavil,Endep,Laroxyl,Lentizol,Novoprotect,Saroten,Sarotex,Syneudon,Triptafen,Tryptanol,Tryptine,Tryptizol,Amitriptylin Neuraxpharm,Apo Amitriptyline,Desitin, Amitriptylin,RPh, Amitriptylin
D000929 Antidepressive Agents, Tricyclic Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. Antidepressants, Tricyclic,Tricyclic Antidepressant,Tricyclic Antidepressant Drug,Tricyclic Antidepressive Agent,Tricyclic Antidepressive Agents,Antidepressant Drugs, Tricyclic,Agent, Tricyclic Antidepressive,Agents, Tricyclic Antidepressive,Antidepressant Drug, Tricyclic,Antidepressant, Tricyclic,Antidepressive Agent, Tricyclic,Drug, Tricyclic Antidepressant,Drugs, Tricyclic Antidepressant,Tricyclic Antidepressant Drugs,Tricyclic Antidepressants
D018781 Tension-Type Headache A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) Headache, Tension,Psychogenic Headache,Stress Headache,Tension-Vascular Headache,Idiopathic Headache,Tension Headache,Headache, Idiopathic,Headache, Psychogenic,Headache, Stress,Headache, Tension-Type,Headache, Tension-Vascular,Headaches, Idiopathic,Headaches, Psychogenic,Headaches, Stress,Headaches, Tension,Headaches, Tension-Type,Headaches, Tension-Vascular,Idiopathic Headaches,Psychogenic Headaches,Stress Headaches,Tension Headaches,Tension Type Headache,Tension Vascular Headache,Tension-Type Headaches,Tension-Vascular Headaches
D020773 Headache Disorders Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) Cephalgia Syndromes,Chronic Headache,Chronic Daily Headache,Headache Syndromes,Headache, Intractable,Cephalgia Syndrome,Chronic Daily Headaches,Chronic Headaches,Daily Headache, Chronic,Daily Headaches, Chronic,Headache Disorder,Headache Syndrome,Headache, Chronic,Headache, Chronic Daily,Headaches, Chronic,Headaches, Chronic Daily,Headaches, Intractable,Intractable Headache,Intractable Headaches,Syndrome, Headache

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