BIOMAT Database Logo BIOMAT Database Logo

[Persistent hyperinsulinemic hypoglycemia. Two case reports]. 2004

Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Servicio de Medicina Interna, Hospital Infantil del Estado de Sonora. nsotelo@hmo.megared.net.mx

We report two cases of infants who presented seizures and persistent hypoglycemia. In both infants, we established diagnosis of persistent hypoglycemia by hyperinsulinism (PHH); glycemic/insulinic ratio was > 0.3, and we found no pancreatic changes by means of other diagnostic procedures. The medical treatment consisted of hydrocortisone, diazoxide, and octreotide without response. Definitive treatment made was sub-total pancreatectomy; postoperatory evolution was satisfactory, and the histologic report showed changes in Langerhans islet of nesidioblastosis. We conclude that PHH and glucose/insulin ratio > 0.3 indicates that surgical treatment with pancreatectomy should not be delayed.

UI MeSH Term Description Entries
D007003 Hypoglycemia A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. Fasting Hypoglycemia,Postabsorptive Hypoglycemia,Postprandial Hypoglycemia,Reactive Hypoglycemia,Hypoglycemia, Fasting,Hypoglycemia, Postabsorptive,Hypoglycemia, Postprandial,Hypoglycemia, Reactive
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006946 Hyperinsulinism A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS. Compensatory Hyperinsulinemia,Endogenous Hyperinsulinism,Exogenous Hyperinsulinism,Hyperinsulinemia,Hyperinsulinemia, Compensatory,Hyperinsulinism, Endogenous,Hyperinsulinism, Exogenous

Related Publications

Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Neonatal hyperinsulinemic hypoglycemia. Two case reports.
August 2002, Minerva pediatrica,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
[Persistent hyperinsulinemic hypoglycemia of infancy: case report]
January 2000, Jornal de pediatria,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Persistent hyperinsulinemic hypoglycemia of infancy.
January 1997, Cancer treatment and research,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Persistent hyperinsulinemic hypoglycemia of infancy.
November 2003, American journal of medical genetics. Part A,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Persistent hyperinsulinemic hypoglycemia of infancy.
April 1998, Indian pediatrics,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Persistent hyperinsulinemic hypoglycemia of infancy.
January 2012, Journal of pediatric endocrinology & metabolism : JPEM,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Facial appearance in persistent hyperinsulinemic hypoglycemia.
August 2002, American journal of medical genetics,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
[Persistent hyperinsulinemic hypoglycemia of the neonate].
October 2004, Srpski arhiv za celokupno lekarstvo,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
[Persistent hyperinsulinemic hypoglycemia of infancy (PHHI)].
November 1997, Nihon rinsho. Japanese journal of clinical medicine,
Norberto Sotelo-Cruz, and Andrés Cordero-Olivares, and Carlos Ramírez-Rodríguez, and Guillermo López-Cervantes, and Jaime Hurtado-Valenzuela, and Brenda María López-Cervantes
Persistent hyperinsulinemic hypoglycemia of infancy - nesidioblastosis.
August 2004, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP,
Copied contents to your clipboard!