Biomaterial Database

Influence of dietary fat polyunsaturated to saturated ratio on energy substrate utilization in obesity. 1992

P J Jones, and J E Ridgen, and P T Phang, and C L Birmingham

Division of Human Nutrition, University of British Columbia, Vancouver, Canada.

The effect of the polyunsaturated to saturated (P:S) ratio of dietary fat on preprandial and postprandial macronutrient oxidation was studied in normal-weight and obese individuals. Total thermogenic response and fat and carbohydrate oxidation rates were determined by duplicate respiratory gas exchange measurements after test breakfasts, in seven normal and eight overweight subjects who consumed self-selected diets containing fat of high or low P:S ratio. Dietary intake records and erythrocyte linoleic to oleic (L:O) acid ratio changes were used as indicators of dietary compliance. No diet- or weight-related differences were observed in resting fat or carbohydrate oxidation rates, or in protein-free basal energy expenditure. Obese subjects consuming low P:S ratio diets exhibited reduced (P less than .05) contribution of fat oxidation to the thermogenic response, compared with lean individuals consuming high or low P:S ratio diets. However, total calories associated with the thermogenic response, and total fat and carbohydrate oxidation after the test breakfasts, did not differ significantly across groups. These findings suggest that, in obesity, whole-body postprandial disposal of dietary fat is influenced by the long-chain fatty acid composition.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009765	Obesity	A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D001831	Body Temperature	The measure of the level of heat of a human or animal.	Organ Temperature,Body Temperatures,Organ Temperatures,Temperature, Body,Temperature, Organ,Temperatures, Body,Temperatures, Organ
D002149	Energy Intake	Total number of calories taken in daily whether ingested or by parenteral routes.	Caloric Intake,Calorie Intake,Intake, Calorie,Intake, Energy
D004041	Dietary Fats	Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.	Fats, Dietary,Dietary Fat,Fat, Dietary
D004435	Eating	The consumption of edible substances.	Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D004734	Energy Metabolism	The chemical reactions involved in the production and utilization of various forms of energy in cells.	Bioenergetics,Energy Expenditure,Bioenergetic,Energy Expenditures,Energy Metabolisms,Expenditure, Energy,Expenditures, Energy,Metabolism, Energy,Metabolisms, Energy
D004912	Erythrocytes	Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.	Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle