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Prevention of intraventricular hemorrhage by indomethacin in male preterm infants. 2004
Laura R Ment, and
Betty R Vohr, and
Robert W Makuch, and
Michael Westerveld, and
Karol H Katz, and
Karen C Schneider, and
Charles C Duncan, and
Richard Ehrenkranz, and
William Oh, and
Alistair G S Philip, and
David T Scott, and
Walter C Allan
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA. Laura.ment@yale.edu
Our multicenter Indomethacin Intraventricular Hemorrhage (IVH) Prevention Trial demonstrated a reduction of IVH in preterm infants. Analysis of our cohort by sex showed indomethacin halved the incidence of IVH, eliminated parenchymal hemorrhage, and was associated with higher verbal scores at 3 to 8 years in boys.
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