Biomaterial Database

Use of live nonhuman primates in research in Asia. 2004

J Hagelin

Synalsvagen 10, SE 757 57 Uppsala, Sweden. joakim.hagelin@hsl.gov.uk

BACKGROUND Use of live non-human primates (NHPs) in biomedical research is a controversial issue in many parts of the world. Recent use of NHPs in research in Asian countries was surveyed. OBJECTIVE To elucidate the use of NHPs in research in Asian countries. METHODS The peer-reviewed literature was sampled according to the species used, area of research, research class and geographic location. Articles derived from database searches were scrutinised. METHODS Studies were identified from the PrimateLit database. CONCLUSIONS Results suggested that NHP research was conducted in 16 countries, of which Japan accounted for two-thirds. About 55% of studies involved use of live animals, whereas the remaining 45% used some lower level of biological material. More than 70% of the studies using live NHPs included use of Old World monkeys. M. fuscata (18%), M. mulatta (17%) and M. fascicularis (10%) were the three most commonly used species. The most common research areas were neuroscience (44%), conservation (14%) and behaviour (11%). Due to high demand for NHPs, there is room for increased breeding of NHPs to be used for research in Asian countries.

UI	MeSH Term	Description	Entries
D011323	Primates	An order of mammals consisting of more than 300 species that include LEMURS; LORISIDAE; TARSIERS; MONKEYS; and HOMINIDS. They are characterized by a relatively large brain when compared with other terrestrial mammals, forward-facing eyes, the presence of a CALCARINE SULCUS, and specialized MECHANORECEPTORS in the hands and feet which allow the perception of light touch.	Primate
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001208	Asia	The largest of the continents. It was known to the Romans more specifically as what we know today as Asia Minor. The name comes from at least two possible sources: from the Assyrian asu (to rise) or from the Sanskrit usa (dawn), both with reference to its being the land of the rising sun, i.e., eastern as opposed to Europe, to the west. (From Webster's New Geographical Dictionary, 1988, p82 & Room, Brewer's Dictionary of Names, 1992, p34)
D032761	Animal Experimentation	The use of animals as investigational subjects.	Animal Experimental Use,Animal Experiments,Animal Research,Animal Experiment,Animal Experimental Uses,Experiment, Animal,Experimental Use, Animal,Experimental Uses, Animal,Experimentation, Animal,Experiments, Animal,Research, Animal