7-Vinyl-8-aza-7-deaza-2'-deoxyadenosine monohydrate. 2005

Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Barbarastrasse 7, 49069 Osnabrück, Germany. frank.seela@uni-osnabrueck.de

In the title compound, 4-amino-1-(2-deoxy-beta-D-eythro-pentofuranosyl)-3-vinyl-1H-pyrazolo[3,4-d]pyrimidine monohydrate, C12H15N5O3.H2O, the conformation of the glycosyl bond is anti. The furanose moiety is in an S conformation with an unsymmetrical twist, and the conformation at the exocyclic C-C(OH) bond is +sc (gauche, gauche). The vinyl side chain is bent out of the heterocyclic ring plane by 147.5 (5) degrees . The three-dimensional packing is stabilized by O-H...O, O-H...N and N-H...O hydrogen bonds.

UI MeSH Term Description Entries
D003839 Deoxyadenosines Adenosine molecules which can be substituted in any position, but are lacking one hydroxyl group in the ribose part of the molecule. Adenine Deoxyribonucleosides,Adenylyldeoxyribonucleosides,Deoxyadenosine Derivatives,Deoxyribonucleosides, Adenine,Derivatives, Deoxyadenosine
D006860 Hydrogen Bonding A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds. Hydrogen Bonds,Bond, Hydrogen,Hydrogen Bond
D001372 Aza Compounds Organic chemicals where carbon atoms have been replaced by nitrogen atoms. Compounds, Aza
D014753 Vinyl Compounds Compounds containing the vinyl (-C Compounds, Vinyl
D014867 Water A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Hydrogen Oxide
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D018360 Crystallography, X-Ray The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) X-Ray Crystallography,Crystallography, X Ray,Crystallography, Xray,X Ray Crystallography,Xray Crystallography,Crystallographies, X Ray,X Ray Crystallographies

Related Publications

Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
April 2000, Acta crystallographica. Section C, Crystal structure communications,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
September 2005, Acta crystallographica. Section C, Crystal structure communications,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
April 2005, Acta crystallographica. Section C, Crystal structure communications,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
August 1996, Nucleic acids research,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
March 2019, Molecules (Basel, Switzerland),
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
January 2014, Organic & biomolecular chemistry,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
December 2014, Acta crystallographica. Section C, Structural chemistry,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
August 2011, Organic & biomolecular chemistry,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
February 1989, Nucleic acids research,
Frank Seela, and Yunlong Zhang, and Kuiying Xu, and Henning Eickmeier
January 2000, Nucleosides, nucleotides & nucleic acids,
Copied contents to your clipboard!