[Arterial complications after renal transplantation]. 2004

Michel Lacombe
Hôpital Beaujon, 92118 Clichy cedex.

We report our experience of surgical treatment of arterial complications after renal transplantation, in 154 patients operated on between 1970 and 2003. The arterial complication was discovered during a routine post-transplant check-up, or when the patient developed clinical manifestations (arterial hypertension, impaired renal function, arterial symptoms in the lower limbs), or following a septic complication. The following lesions were surgically managed: mycotic aneurysms (N = 5), atherosclerotic aneurysms (N = 13) or obstructions (N = 11) of the aorta and iliac arteries, and stenoses of the artery supplying the grafted kidney (N = 125). The type of arterial repair depended on the complication. There were no postoperative deaths. Three thromboses occurred after reconstruction of a stenotic transplant artery (3/125, 2.4 %), leading to graft loss. During long-term follow-up, atherosclerotic lesions of the iliac arteries worsened below an aortic prosthesis in three patients who required repeated surgery. In two other patients, stenosis recurred on a transplant artery and required re-operation. In one patient, an aneurysm developed in a vein graft and was successfully replaced by an arterial autograft. Late deaths among atherosclerotic patients in this setting are usually due to cardiac causes. In all patients, late chronic rejection may lead to kidney loss and hemodialysis.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012078 Renal Artery Obstruction Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR). Renal Artery Stenosis,Obstruction, Renal Artery,Obstructions, Renal Artery,Renal Artery Obstructions,Renal Artery Stenoses,Stenoses, Renal Artery,Stenosis, Renal Artery
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000785 Aneurysm, Infected Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms. Aneurysm, Bacterial,Aneurysm, Mycotic,Mycotic Aneurysm,Bacterial Aneurysm,Bacterial Aneurysms,Fungal Aneurysm,Infected Aneurysm,Aneurysm, Fungal,Aneurysms, Bacterial,Aneurysms, Fungal,Aneurysms, Infected,Aneurysms, Mycotic,Fungal Aneurysms,Infected Aneurysms,Mycotic Aneurysms
D001161 Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. Arterioscleroses
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D016030 Kidney Transplantation The transference of a kidney from one human or animal to another. Grafting, Kidney,Renal Transplantation,Transplantation, Kidney,Transplantation, Renal,Kidney Grafting,Kidney Transplantations,Renal Transplantations,Transplantations, Kidney,Transplantations, Renal
D017543 Iliac Aneurysm Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY. Aneurysm, Iliac,Aneurysms, Iliac,Iliac Aneurysms

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