BIOMAT Database Logo BIOMAT Database Logo

Transplantation of porcine fetal islet-like cell clusters to three diabetic patients. 1992

A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Department of Medical Cell Biology, Uppsala University, Sweden.

UI MeSH Term Description Entries
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D010976 Platelet Count The number of PLATELETS per unit volume in a sample of venous BLOOD. Blood Platelet Count,Blood Platelet Number,Platelet Number,Blood Platelet Counts,Blood Platelet Numbers,Count, Blood Platelet,Count, Platelet,Counts, Blood Platelet,Counts, Platelet,Number, Blood Platelet,Number, Platelet,Numbers, Blood Platelet,Numbers, Platelet,Platelet Count, Blood,Platelet Counts,Platelet Counts, Blood,Platelet Number, Blood,Platelet Numbers,Platelet Numbers, Blood
D002096 C-Peptide The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin. Proinsulin C-Peptide,C-Peptide, Proinsulin,Connecting Peptide,C Peptide,C Peptide, Proinsulin,Proinsulin C Peptide
D003922 Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. Diabetes Mellitus, Brittle,Diabetes Mellitus, Insulin-Dependent,Diabetes Mellitus, Juvenile-Onset,Diabetes Mellitus, Ketosis-Prone,Diabetes Mellitus, Sudden-Onset,Diabetes, Autoimmune,IDDM,Autoimmune Diabetes,Diabetes Mellitus, Insulin-Dependent, 1,Diabetes Mellitus, Type I,Insulin-Dependent Diabetes Mellitus 1,Juvenile-Onset Diabetes,Type 1 Diabetes,Type 1 Diabetes Mellitus,Brittle Diabetes Mellitus,Diabetes Mellitus, Insulin Dependent,Diabetes Mellitus, Juvenile Onset,Diabetes Mellitus, Ketosis Prone,Diabetes Mellitus, Sudden Onset,Diabetes, Juvenile-Onset,Diabetes, Type 1,Insulin Dependent Diabetes Mellitus 1,Insulin-Dependent Diabetes Mellitus,Juvenile Onset Diabetes,Juvenile-Onset Diabetes Mellitus,Ketosis-Prone Diabetes Mellitus,Sudden-Onset Diabetes Mellitus
D005260 Female Females
D005340 Fibrinogen Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000410 Alanine Transaminase An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2. Alanine Aminotransferase,Glutamic-Pyruvic Transaminase,SGPT,Alanine-2-Oxoglutarate Aminotransferase,Glutamic-Alanine Transaminase,Alanine 2 Oxoglutarate Aminotransferase,Aminotransferase, Alanine,Aminotransferase, Alanine-2-Oxoglutarate,Glutamic Alanine Transaminase,Glutamic Pyruvic Transaminase,Transaminase, Alanine,Transaminase, Glutamic-Alanine,Transaminase, Glutamic-Pyruvic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
In vitro dedifferentiation of fetal porcine pancreatic tissue prior to transplantation as islet-like cell clusters.
January 2001, Cells, tissues, organs,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Angiogenesis and angioarchitecture of transplanted fetal porcine islet-like cell clusters.
December 1999, Transplantation,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: an immunohistochemical study.
March 1999, Transplantation,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Increased anti-Gal activity in diabetic patients transplanted with fetal porcine islet cell clusters.
June 1995, Transplantation,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice.
June 1991, Diabetologia,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Polyamine requirements in nicotinamide-stimulated beta-cell differentiation in fetal porcine islet-like cell clusters.
October 1994, Endocrinology,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Transplantation of porcine fetal pancreas to diabetic patients.
March 1995, Lancet (London, England),
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Transplantation of porcine fetal pancreas to diabetic patients.
January 1995, Lancet (London, England),
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Transfer of immunocompetent cells to athymic nude mice previously transplanted with fetal porcine islet-like cell clusters.
January 1997, Transplantation proceedings,
A Andersson, and C G Groth, and O Korsgren, and A Tibell, and J Tollemar, and M Kumagai, and E Möller, and J Bolinder, and J Ostman, and A Bjöersdorff
Characterisation and origin of pig fetal islet-like cell clusters.
December 1995, Transplantation proceedings,
Copied contents to your clipboard!