[Separation of aromatic amines by capillary zone electrophoresis with lower electroosmotic flow]. 2004

Fu Huang, and Shengquan Ye
Department of Applied Chemistry, Zhanjiang Ocean University, Zhanjiang 524006, China.

It is effective to restrain the electroosmotic flow (EOF) with lower pH value (pH < or = 2.0). As a result, a capillary zone electrophoretic (CZE) system of lower electroosmotic flow was established. Seven aromatic amines were separated by CZE with lower electroosmotic flow. In the system, the aromatic amines combined with protons under the experimental conditions, and had positive charges. Therefore, the sample entered the capillary at the positive electrode and was detected at the negative electrode. It was found that the migration time of aromatic amines increased quickly with a slight increase in pH value in CZE at lower electroosmotic flow. The retention order of peaks of aromatic amines is related to their pKb and the numbers of amino and acidic groups. When the number of amino groups gets larger, the pKb becomes smaller, and the peaks elute earlier. The acidic groups of aromatic amines make the peaks to elute later. The optimal conditions were 40 mmol/L NaH2PO4 (pH 1.7).

UI MeSH Term Description Entries
D009995 Osmosis Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane. Osmoses
D004553 Electric Conductivity The ability of a substrate to allow the passage of ELECTRONS. Electrical Conductivity,Conductivity, Electric,Conductivity, Electrical
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D000588 Amines A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed) Amine
D000814 Aniline Compounds Compounds that include the aminobenzene structure. Phenylamine,Phenylamines,Anilines,Compounds, Aniline
D001560 Benzidines Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species. Bianilines,Biphenyldiamines
D013499 Surface Properties Characteristics or attributes of the outer boundaries of objects, including molecules. Properties, Surface,Property, Surface,Surface Property
D019075 Electrophoresis, Capillary A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992) Capillary Zone Electrophoresis,Capillary Electrophoreses,Capillary Electrophoresis,Capillary Zone Electrophoreses,Electrophoreses, Capillary,Electrophoreses, Capillary Zone,Electrophoresis, Capillary Zone,Zone Electrophoreses, Capillary,Zone Electrophoresis, Capillary

Related Publications

Fu Huang, and Shengquan Ye
November 1995, Electrophoresis,
Fu Huang, and Shengquan Ye
April 2021, Electrophoresis,
Fu Huang, and Shengquan Ye
August 1993, Analytical chemistry,
Fu Huang, and Shengquan Ye
April 1993, Journal of chromatography,
Fu Huang, and Shengquan Ye
October 1989, Journal of chromatography,
Copied contents to your clipboard!