UK audit of left ventricular ejection fraction estimation from equilibrium ECG gated blood pool images. 2005

John V Skrypniuk, and Dale Bailey, and Philip S Cosgriff, and John S Fleming, and Alex S Houston, and Peter H Jarritt, and David R Whalley
IPEM Nuclear Medicine Software Working Party, York, UK. john.skrypniuk@nnuh.nhs.uk

OBJECTIVE To examine the variability of results obtained from computer analysis of left ventricular gated blood pool (LVGBP) images by nuclear medicine centres in the UK. METHODS Twelve data sets of LVGBP images were distributed via commercial software suppliers to nuclear medicine centres in the UK. Two of the data sets were duplicates and three were acquired from the same patient with different total counts in the images. The quality of the images was also variable and two images had poorly defined left ventricular walls. A questionnaire was used to identify the parameters used during the analysis and to give an indication of the number of LVGBP scans per year routinely carried out by each centre as well as report the results obtained from the analysis. RESULTS Results were received from 63 nuclear medicine centres using 77 computer systems. The vast majority of participants (57) carried out fewer than 10 scans per month. Only two centres performed more than 30 scans per month. Sixteen centres did not quote a minimum normal value for left ventricular ejection fraction (LVEF) and 36 did not record a maximum value. The remainder recorded between 0.40 and 0.60 for the minimum of normal range and 0.60-0.90 for the maximum of normal range. Analysis of returns showed that LVEF estimates for the data sets were highly variable between centres and computer systems. The overall standard deviation of results compared to the mean for each study was 0.076. Approximately half this variation was due to systematic variation between centres. The overall precision taking into consideration this systematic variation, was 0.055. Lower variability was found between studies with higher overall counts and this was highly significant.

UI MeSH Term Description Entries
D007090 Image Interpretation, Computer-Assisted Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease. Image Interpretation, Computer Assisted,Computer-Assisted Image Interpretation,Computer-Assisted Image Interpretations,Image Interpretations, Computer-Assisted,Interpretation, Computer-Assisted Image,Interpretations, Computer-Assisted Image
D008485 Medical Audit A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care. Audit, Medical,Audits, Medical,Medical Audits
D011785 Quality Assurance, Health Care Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps. Quality Assessment, Health Care,Health Care Quality Assessment,Health Care Quality Assurance,Healthcare Quality Assessment,Healthcare Quality Assurance,Quality Assessment, Healthcare,Quality Assurance, Healthcare,Assessment, Healthcare Quality,Assessments, Healthcare Quality,Assurance, Healthcare Quality,Assurances, Healthcare Quality,Healthcare Quality Assessments,Healthcare Quality Assurances,Quality Assessments, Healthcare,Quality Assurances, Healthcare
D006113 United Kingdom Country in northwestern Europe including Great Britain and the northern one-sixth of the island of Ireland, located between the North Sea and north Atlantic Ocean. The capital is London. Great Britain,Isle of Man
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D013318 Stroke Volume The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume. Ventricular Ejection Fraction,Ventricular End-Diastolic Volume,Ventricular End-Systolic Volume,Ejection Fraction, Ventricular,Ejection Fractions, Ventricular,End-Diastolic Volume, Ventricular,End-Diastolic Volumes, Ventricular,End-Systolic Volume, Ventricular,End-Systolic Volumes, Ventricular,Fraction, Ventricular Ejection,Fractions, Ventricular Ejection,Stroke Volumes,Ventricular Ejection Fractions,Ventricular End Diastolic Volume,Ventricular End Systolic Volume,Ventricular End-Diastolic Volumes,Ventricular End-Systolic Volumes,Volume, Stroke,Volume, Ventricular End-Diastolic,Volume, Ventricular End-Systolic,Volumes, Stroke,Volumes, Ventricular End-Diastolic,Volumes, Ventricular End-Systolic
D015203 Reproducibility of Results The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results. Reliability and Validity,Reliability of Result,Reproducibility Of Result,Reproducibility of Finding,Validity of Result,Validity of Results,Face Validity,Reliability (Epidemiology),Reliability of Results,Reproducibility of Findings,Test-Retest Reliability,Validity (Epidemiology),Finding Reproducibilities,Finding Reproducibility,Of Result, Reproducibility,Of Results, Reproducibility,Reliabilities, Test-Retest,Reliability, Test-Retest,Result Reliabilities,Result Reliability,Result Validities,Result Validity,Result, Reproducibility Of,Results, Reproducibility Of,Test Retest Reliability,Validity and Reliability,Validity, Face
D015588 Observer Variation The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material). Bias, Observer,Interobserver Variation,Intraobserver Variation,Observer Bias,Inter-Observer Variability,Inter-Observer Variation,Interobserver Variability,Intra-Observer Variability,Intra-Observer Variation,Intraobserver Variability,Inter Observer Variability,Inter Observer Variation,Inter-Observer Variabilities,Inter-Observer Variations,Interobserver Variabilities,Interobserver Variations,Intra Observer Variability,Intra Observer Variation,Intra-Observer Variabilities,Intra-Observer Variations,Intraobserver Variabilities,Intraobserver Variations,Observer Variations,Variabilities, Inter-Observer,Variabilities, Interobserver,Variabilities, Intra-Observer,Variabilities, Intraobserver,Variability, Inter-Observer,Variability, Interobserver,Variability, Intra-Observer,Variability, Intraobserver,Variation, Inter-Observer,Variation, Interobserver,Variation, Intra-Observer,Variation, Intraobserver,Variation, Observer,Variations, Inter-Observer,Variations, Interobserver,Variations, Intra-Observer,Variations, Intraobserver,Variations, Observer
D015637 Gated Blood-Pool Imaging Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS). Angiography, Gated Radionuclide,Equilibrium Radionuclide Angiography,Equilibrium Radionuclide Ventriculography,Gated Blood-Pool Scintigraphy,Gated Equilibrium Blood-Pool Scintigraphy,Radionuclide Angiography, Gated,Radionuclide Ventriculography, Gated,Scintigraphy, Equilibrium,Ventriculography, Equilibrium Radionuclide,Ventriculography, Gated Radionuclide,Blood-Pool Scintigraphy,Equilibrium Radionuclide Angiocardiography,Gated Equilibrium Blood Pool Scintigraphy,Angiocardiographies, Equilibrium Radionuclide,Angiocardiography, Equilibrium Radionuclide,Angiographies, Equilibrium Radionuclide,Angiographies, Gated Radionuclide,Angiography, Equilibrium Radionuclide,Blood Pool Scintigraphy,Blood-Pool Imaging, Gated,Blood-Pool Imagings, Gated,Blood-Pool Scintigraphies,Blood-Pool Scintigraphies, Gated,Blood-Pool Scintigraphy, Gated,Equilibrium Radionuclide Angiocardiographies,Equilibrium Radionuclide Angiographies,Equilibrium Radionuclide Ventriculographies,Equilibrium Scintigraphies,Equilibrium Scintigraphy,Gated Blood Pool Imaging,Gated Blood Pool Scintigraphy,Gated Blood-Pool Imagings,Gated Blood-Pool Scintigraphies,Gated Radionuclide Angiographies,Gated Radionuclide Angiography,Gated Radionuclide Ventriculographies,Gated Radionuclide Ventriculography,Imaging, Gated Blood-Pool,Imagings, Gated Blood-Pool,Radionuclide Angiocardiographies, Equilibrium,Radionuclide Angiocardiography, Equilibrium,Radionuclide Angiographies, Equilibrium,Radionuclide Angiographies, Gated,Radionuclide Angiography, Equilibrium,Radionuclide Ventriculographies, Equilibrium,Radionuclide Ventriculographies, Gated,Radionuclide Ventriculography, Equilibrium,Scintigraphies, Blood-Pool,Scintigraphies, Equilibrium,Scintigraphies, Gated Blood-Pool,Scintigraphy, Blood-Pool,Scintigraphy, Gated Blood-Pool,Ventriculographies, Equilibrium Radionuclide,Ventriculographies, Gated Radionuclide

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