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Chronic immune complex formation was induced in rabbits by daily administration of 12.5 g bovine serum. In good antibody producer animals immediate immune complex production and elimination from the circulation were demonstrable. This was followed within a few minutes by the appearance of free 125I in fairly large amounts in blood, as a sign of immediate phagocytosis and disintegration of the 125I-labelled immune complexes. Phagocytic activity decreased in the host animal during chronic heteroprotein administration in every case. The earliest glomerular changes were those of exudative glomerulonephritis, the extent of which depended on the antibody productivity of the animal. Persistent immunocomplexaemia induced by administration of the antigen over 60 and 100 days, respectively, resulted in mesangioproliferative glomerulonephritis in 7, in membranoproliferative glomerulonephritis in 3, and in membraneous glomerulonephritis in 1 out of 11 laboratory animals.
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
November 1986,
Kidney international,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
July 1991,
The Journal of pathology,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
December 1980,
The Japanese journal of experimental medicine,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
March 1999,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
August 1979,
Kidney international,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
April 1967,
The Johns Hopkins medical journal,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
January 1980,
Kidney international,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
April 1979,
Laboratory investigation; a journal of technical methods and pathology,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
January 1976,
Laboratory investigation; a journal of technical methods and pathology,
T Szabó, and
J Szabó, and
C Balázs, and
G Lustyik
January 1992,
Nephron,
