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Peripolesis is a phenomenon in which a lymphocyte attaches itself to another cell, usually a macrophage or veiled cell, and proceeds to circle around it. In emperipolesis, a related phenomenon, the lymphocyte invaginates the target cell so deeply that it appears to be intracytoplasmic. Lung cells in bronchoalveolar lavage fluids from 20 patients were observed in the living state and filmed. Peripolesis of the alveolar macrophages was recorded in six cases. These patients included one case each of carcinoma of the bronchus, tuberculosis, sarcoidosis and asthma, while two patients had no detectable lung disease. Five out of the six positive cases were females. In every instance there was a high number of lymphocytes in the washing. The peripolesed macrophages were not injured, but temporary alteration of the cell membrane was noted in a minority of film sequences. The peripolesing cells were also examined by transmission and scanning electron microscopy. The lymphocyte was found to be closely attached to the surface of the macrophage, with no invagination and its ultrastructure was that of a small lymphocyte. Peripolesis is probably a physiological mechanism concerned with regulation of the immune response in the lung.
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
August 1965,
Lancet (London, England),
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
May 1993,
The American review of respiratory disease,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
June 1986,
The American review of respiratory disease,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
January 1981,
Immunology,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
January 1979,
Advances in experimental medicine and biology,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
September 1981,
JAMA,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
May 2011,
Seminars in immunopathology,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
June 1999,
The Journal of laboratory and clinical medicine,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
January 1977,
Journal of the Reticuloendothelial Society,
D J Lyons, and
A Gautam, and
J Clark, and
M G Harries, and
E B Mitchell, and
J S Milledge, and
B M Balfour
October 1968,
Experimental cell research,
