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Five hundred and sixty-three primary cutaneous melanomas were assessed for the presence of histological regression in relation to the thickness of the lesion and features such as sex, anatomical location and clinical outcome. Regression was more common in thin lesions, being seen in 46% of thin (less than 1.5 mm) lesions, 32% of intermediate (1.5-3.0 mm) lesions and 9% of thick (greater than 3.0 mm) lesions. However, severe regression was only identified in 6.5% of thin lesions, 5.2% of intermediate lesions and 1.5% of thick melanomas. Regression was more common in superficial spreading melanomas and in lesions from the trunk and lower limb. Moderate and severe regression were seen slightly more often in men. Clinical follow-up, although not of statistical significance, suggests that regression in thin lesions is a sinister histological feature.
K Blessing, and
K M McLaren
June 2017,
Laboratory investigation; a journal of technical methods and pathology,
K Blessing, and
K M McLaren
January 2021,
Clinical and experimental dermatology,
K Blessing, and
K M McLaren
December 2017,
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia,
K Blessing, and
K M McLaren
February 2018,
The British journal of dermatology,
K Blessing, and
K M McLaren
July 2022,
Medicine and pharmacy reports,
K Blessing, and
K M McLaren
January 2021,
Archives of dermatological research,
K Blessing, and
K M McLaren
March 2023,
Pathology,
K Blessing, and
K M McLaren
January 1982,
Hospital practice (Office ed.),
K Blessing, and
K M McLaren
July 1992,
Melanoma research,
K Blessing, and
K M McLaren
May 1997,
Archives of surgery (Chicago, Ill. : 1960),
