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The creation of a physical map of chromosome 18 will be useful for the eventual identification of specific chromosomal regions that are critical in the occurrence of Edwards syndrome, the 18q- syndrome, and the 18p- syndrome. To begin the investigation of these syndromes, a physical map has been constructed to order random DNA fragments to specific portions of chromosome 18. A set of somatic cell hybrids that retain deletions or translocations involving chromosome 18 has been isolated and characterized. Over 200 lambda phage from a chromosome 18-specific library have been localized to 11 distinct regions of chromosome 18 using the chromosomal breakpoints present in the somatic cell hybrids.
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
December 1993,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
January 1994,
Cytogenetics and cell genetics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
October 1992,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
January 1995,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
September 1991,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
June 2003,
Animal genetics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
October 1996,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
January 1994,
European journal of human genetics : EJHG,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
August 1991,
Genomics,
A D Kline, and
K Rojas, and
R Mewar, and
D Moshinsky, and
J Overhauser
October 1972,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
