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[Treatment with vitamin D metabolites for rickets/osteomalacia]. 2003

Yasuhiro Takeuchi
Division of Endocrinology and Nephrology, Department of Medicine, University of Tokyo School of Medicine.

Rickets and osteomalacia is a metabolic bone disease due to a mineralization defect as principal pathophysiology. Since a variety of disorders cause insufficient mineralization of bone, treatment specific to each disorder should be applied to a patient with rickets/osteomalacia. Clinical consensus for medical treatment for rickets/osteomalacia is overviewed in this manuscript. Vitamin D as an anti-rachitic factor and its metabolites play a pivotal role for treatment of patients with rickets/osteomaracia.

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