-transparent.png){kind=logo}
This paper presents a cytogenetic analysis of two established but early-passage (passages 5 and 18) cell lines derived from histologically similar, poorly differentiated lymph node metastases of squamous cell carcinoma of the lung. The cell lines showed 3 shared marker chromosomes, del(1)(q11), del(2)(p11.1) and del(2)(q11.1). One of the lines (DLKP) had 8 additional markers including structural rearrangements such as translocations and isochromosomes. Five additional markers (including two deletions of chromosome 3) were found in DLRP. A notable feature of DLRP was the high incidence of telomeric association evident in the majority of metaphase plates. Over-representation of chromosome 7 was a characteristic feature of metaphases derived from DLKP, and identification of i(21q) in this cell line was an unusual finding. The results indicate significant cytogenetic heterogeneity between these early-passage cell lines derived from two apparently histologically similar tumors.
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
November 1998,
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
February 1998,
Cancer genetics and cytogenetics,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
April 2021,
The Laryngoscope,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
January 2010,
Case reports in medicine,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
December 2007,
Journal of cutaneous pathology,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
April 2013,
Pathology, research and practice,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
July 1999,
International journal of dermatology,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
June 2015,
Annals of dermatology,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
October 2009,
Clinical cancer research : an official journal of the American Association for Cancer Research,
E Law, and
U Gilvarry, and
V Lynch, and
B Gregory, and
G Grant, and
M Clynes
August 1994,
Japanese journal of clinical oncology,
