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Artificial esophagus with peristaltic movement. 2005

Makoto Watanabe, and Kazumitsu Sekine, and Yoshio Hori, and Yasuyuki Shiraishi, and Takeshi Maeda, and Dai Honma, and Go Miyata, and Yoshifumi Saijo, and Tomoyuki Yambe
Department of Medical Engineering and Cardiology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan.

In this study, we have developed an artificial esophagus simulating peristaltic movement with the use of a nickel-titanium shape memory alloy (NiTi-SMA) actuator. Serial pairs of NiTi-SMAs were placed around a Gore-Tex vascular graft in a helical position such that they obliterated the lumen of the vessel when they contracted. In an animal experiment using a goat, the cervical esophagus was resected over a length of approximately 20 cm. The artificial esophagus was anastomosed with the remaining cervical esophagus. When a direct current of 500 mA at 5 V was applied to the NiTi-SMAs, the first pair of the NiTi-SMA contracted. The following pairs of the NiTi-SMAs contracted consecutively. The entire contraction of the artificial esophagus was similar to the esophageal peristaltic movement observed by x-ray examination in humans. The results showed the possibility that the artificial esophagus could function as an artificial esophagus having peristaltic movement.

UI MeSH Term Description Entries
D010528 Peristalsis A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction. Peristalses
D004560 Electricity The physical effects involving the presence of electric charges at rest and in motion.
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D004947 Esophagus The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
D006041 Goats Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP. Capra,Capras,Goat
D000714 Anastomosis, Surgical Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side. Surgical Anastomosis,Anastomoses, Surgical,Surgical Anastomoses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001187 Artificial Organs Devices intended to replace non-functioning organs. They may be temporary or permanent. Since they are intended always to function as the natural organs they are replacing, they should be differentiated from PROSTHESES AND IMPLANTS and specific types of prostheses which, though also replacements for body parts, are frequently cosmetic (EYE, ARTIFICIAL) as well as functional (ARTIFICIAL LIMBS). Artificial Organ,Organ, Artificial,Organs, Artificial
D019563 Mechanics The branch of physics which deals with the motions of material bodies, including kinematics, dynamics, and statics. When the laws of mechanics are applied to living structures, as to the locomotor system, it is referred to as BIOMECHANICAL PHENOMENA. (From Dorland, 28th ed)

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