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The effect of injection or chronic infusion of lipopolysaccharide (LPS) into unanaesthetized rats on the distribution of [99Tcm-]SC has been determined. At a dose of 2.5 mg/kg, LPS injection caused a marked alteration in the distribution of the radiolabelled material, with more uptake being achieved in the lung while less was taken up by the spleen. Kidney and liver uptake were also changed. Chronic infusion of LPS at a similar dose (3 mg/kg in 24 h) caused a marked increase in the uptake of the radioactive material by the lung only. These data are consistent with a working hypothesis that the alterations in RES phagocytic activity of the lung observed in rats subjected to burn trauma could be related in part to LPS, either coming as a bolus, or being continuously presented.
M Trop, and
E J Schiffrin, and
E A Carter
September 1964,
Zentralblatt fur Gynakologie,
M Trop, and
E J Schiffrin, and
E A Carter
January 1977,
Surgical forum,
M Trop, and
E J Schiffrin, and
E A Carter
May 1979,
Journal of the Reticuloendothelial Society,
M Trop, and
E J Schiffrin, and
E A Carter
January 1953,
Rivista dell'Istituto sieroterapico italiano,
M Trop, and
E J Schiffrin, and
E A Carter
January 1963,
Antibiotica et chemotherapia. Fortschritte. Advances. Progres,
M Trop, and
E J Schiffrin, and
E A Carter
January 1970,
Naunyn-Schmiedebergs Archiv fur Pharmakologie,
M Trop, and
E J Schiffrin, and
E A Carter
October 1958,
Acta physiologica Scandinavica,
M Trop, and
E J Schiffrin, and
E A Carter
January 1970,
Fiziologia normala si patologica,
M Trop, and
E J Schiffrin, and
E A Carter
July 1966,
Giornale di gerontologia,
M Trop, and
E J Schiffrin, and
E A Carter
August 1983,
The Journal of laboratory and clinical medicine,
