Effect of pre-operative coagulation testing on intra-operative transfusion requirements in surgical patients. 2005

Shemila Abbasi, and Fauzia A Khan
Department of Anaesthesia, Aga Khan University Hospital, Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan. sabb2000@hotmail.com

OBJECTIVE To assess the value of pre-operative coagulation testing in elective surgical patients, to estimate the frequency of abnormality and the outcome in relation to transfusion. METHODS Observational study. METHODS The study was performed at the Aga Khan University Hospital in main operating room over a period of six months from March to September 1999. METHODS All patients scheduled for elective surgery in which the primary physician had ordered PT (prothrombin time), APTT (activated partial thromboplastin time) and PLT (platelet) count were included. Risk groups were made based on history of coagulation disorders and medications altering coagulation. The patients were also stratified according to age and the frequency of abnormality determined in different groups. RESULTS Five hundred cases were studied. The frequency of abnormalities of PT and APTT were found to have statistically high association with the risk groups based on history. There was significant association between age and abnormal platelets count. Only 8 patients were transfused. CONCLUSIONS Pre-operative coagulation tests should only be ordered in high risk groups based on history and examination.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007430 Intraoperative Care Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests. Care, Intraoperative
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011300 Preoperative Care Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed) Care, Preoperative,Preoperative Procedure,Preoperative Procedures,Procedure, Preoperative,Procedures, Preoperative
D001778 Blood Coagulation Disorders Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions. Coagulation Disorders, Blood,Disorders, Blood Coagulation,Blood Coagulation Disorder,Coagulation Disorder, Blood,Disorder, Blood Coagulation
D001780 Blood Coagulation Tests Laboratory tests for evaluating the individual's clotting mechanism. Coagulation Tests, Blood,Tests, Blood Coagulation,Blood Coagulation Test,Coagulation Test, Blood,Test, Blood Coagulation
D001803 Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children

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