-transparent.png){kind=logo}
Patients using long-term double-lumen silastic jugular catheters for haemodialysis access frequently require oral anticoagulants to maintain patency of the catheter. It may be difficult or impossible to obtain peripheral vein blood samples for PT measurements to regulate the oral anticoagulant dose. Our studies have shown that removal of 3 mls of blood from the catheter limb containing the heparin (to be discarded) followed by 10 mls as a heparin wash-out (to be returned to the patient) allows blood to be taken from the arterial limb of the catheter for PT measurement. The PT measurement obtained from the arterial limb after a 10 ml wash-out is nearly always identical with the PT measurement on blood obtained from a peripheral vein. If the simultaneously measured aPTT is normal the PT is predictably and consistently accurate. If the aPTT is raised due to traces of residual heparin then the PT may be inaccurate and should be repeated. This method is easy and reliable and can be recommended as an aid to regulation of the oral anticoagulant dose.
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
May 1996,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
January 1990,
The International journal of artificial organs,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
August 1982,
Lancet (London, England),
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
March 1975,
Anaesthesia,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
January 1986,
Nephron,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
February 2007,
Annals of surgical oncology,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
January 1999,
West African journal of medicine,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
January 2024,
The Cochrane database of systematic reviews,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
January 2001,
Annals of Saudi medicine,
M Besley, and
A Thomas, and
S Salter, and
Y Y Sang, and
M Vas, and
P R Uldall
December 2009,
Annales de cardiologie et d'angeiologie,
