BIOMAT Database Logo BIOMAT Database Logo

The relation of bone marrow scintigraphy and unilateral bone marrow biopsy in malignant lymphoma. 2005

Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Nuclear Medicine Research Center, Shariati hospital, Tehran University of Medical Sciences, Northern Kargar St, 14114 Tehran, Iran.

To assess the diagnostic role of bone marrow scintigraphy (BMS) for detecting bone marrow infiltration by malignant lymphomas, 47 patients, 14 with malignant Hodgkin's and 33 with non-Hodgkin's lymphoma underwent BMS with 99mTc-sulphur-colloid and also unilateral iliac crest bone marrow biopsy (BMB). BM involvement in BMB was observed in 11 of the 47 patients. Four of these patients also had BMS lesions. Eight patients had BMS lesions not detected by BMB. There was poor agreement between the two modalities (kappa=0.137). Considering BMB as the gold standard, sensitivity, specificity, positive predictive value, negative predictive value and accuracy of BMS were 36%, 77%, 33%, 80%, and 68% respectively. In conclusion, BMS has a high negative predictive value and may be used as a complementary screening test for lymphoma to assess the extent of BM involvement, especially if magnetic resonance imaging-guided biopsy or positron emission tomography studies are not available, as is the case in developing countries.

UI MeSH Term Description Entries
D008223 Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. Germinoblastoma,Lymphoma, Malignant,Reticulolymphosarcoma,Sarcoma, Germinoblastic,Germinoblastic Sarcoma,Germinoblastic Sarcomas,Germinoblastomas,Lymphomas,Lymphomas, Malignant,Malignant Lymphoma,Malignant Lymphomas,Reticulolymphosarcomas,Sarcomas, Germinoblastic
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D001853 Bone Marrow The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells. Marrow,Red Marrow,Yellow Marrow,Marrow, Bone,Marrow, Red,Marrow, Yellow
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity

Related Publications

Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Bone marrow biopsy in staging malignant lymphoma.
October 1990, The Journal of the Association of Physicians of India,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
[Bone marrow biopsy in the staging of malignant lymphoma].
May 1978, Harefuah,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Bone marrow biopsy in the staging of malignant lymphoma.
August 1990, The Journal of the Association of Physicians of India,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Malignant lymphoma: bone marrow imaging versus biopsy.
November 1989, Radiology,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
[Bone marrow and bone scintigraphy in the examination of patients with malignant lymphoma].
October 1988, Orvosi hetilap,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
[Bone marrow biopsy in patients with malignant lymphoma].
February 1984, [Rinsho ketsueki] The Japanese journal of clinical hematology,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Magnetic resonance imaging of bone marrow versus bone marrow biopsy in malignant lymphoma.
January 1999, Pathology oncology research : POR,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
[Proceedings: Histology and biopsy findings of bone marrow in malignant lymphoma].
January 1974, Verhandlungen der Deutschen Gesellschaft fur Pathologie,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Seeding of malignant lymphoma along the tract after bone marrow biopsy.
August 1985, Southern medical journal,
Javad Esmaili, and Seyyed Reza Safaee, and Ramezanali Sharifian, and Shahin Shoeybi, and Ali Gholamrezanezhad
Bone marrow biopsy for staging Hodgkin's lymphoma: the value of bilateral or unilateral trephine biopsy.
February 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
Copied contents to your clipboard!