BIOMAT Database Logo BIOMAT Database Logo

Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis. 2005

Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas-Houston Medical School, 77030, USA.

Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.

UI MeSH Term Description Entries
D007121 Immunocompetence The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen. Competence, Immunologic,Immunologic Competence,Immunological Competence,Competence, Immunological
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011933 Reagent Kits, Diagnostic Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use. Diagnostic Reagent Kits,Diagnostic Reagents and Test Kits,Diagnostic Test Kits,In Vitro Diagnostic Device,In Vitro Diagnostic Devices,In Vitro Diagnostic Medical Device,In Vitro Diagnostic Medical Devices,Kits, Diagnostic Reagent,Diagnostic Reagent Kit,Diagnostic Test Kit,Kit, Diagnostic Reagent,Kit, Diagnostic Test,Kits, Diagnostic Test,Reagent Kit, Diagnostic,Test Kit, Diagnostic,Test Kits, Diagnostic
D002175 Candida A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; VULVOVAGINAL CANDIDIASIS; and CANDIDIASIS, ORAL (THRUSH). Candida guilliermondii var. nitratophila,Candida utilis,Cyberlindnera jadinii,Hansenula jadinii,Lindnera jadinii,Monilia,Pichia jadinii,Saccharomyces jadinii,Torula utilis,Torulopsis utilis,Monilias
D002177 Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed) Candida Infection,Moniliasis,Candida Infections,Candidiases,Infection, Candida,Moniliases
D004797 Enzyme-Linked Immunosorbent Assay An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000908 Antibodies, Fungal Immunoglobulins produced in a response to FUNGAL ANTIGENS. Fungal Antibodies
D000946 Antigens, Fungal Substances of fungal origin that have antigenic activity. Fungal Antigen,Fungal Antigens,Antigen, Fungal
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity

Related Publications

Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Diagnosis of invasive candidiasis by a dot immunobinding assay for Candida antigen detection.
March 1993, Journal of clinical microbiology,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Evaluation of three serological tests for detection of anti-candidal antibodies in diagnosis of invasive candidiasis.
April 1994, Mycopathologia,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
IgG1 anti-cell wall and IgG2 anti-phosphopeptidomannan antibodies in the diagnosis of invasive candidiasis and heavy Candida colonization.
September 2015, Medical mycology,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Immunoglobulin E anti-Candida antibodies and candidiasis.
October 1977, Infection and immunity,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Detection of antibodies to Candida albicans germ tubes for diagnosis and therapeutic monitoring of invasive candidiasis in patients with hematologic malignancies.
December 1997, Journal of clinical microbiology,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Circulating Candida-specific anti-mannan antibodies precede invasive candidiasis in patients undergoing myelo-ablative chemotherapy.
April 2009, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
[Detection of circulating Candida albicans mannan and antimannan antibodies: useful for diagnosis of deep seated candidiasis].
January 2002, Annales de biologie clinique,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Detection of antibodies to Candida albicans germ tube in the diagnosis of systemic candidiasis.
April 1987, European journal of clinical microbiology,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Candida antigen latex test for detection of invasive candidiasis in immunocompromised patients.
March 1989, The Journal of infectious diseases,
Annie Philip, and Zekaver Odabasi, and Gloria Matiuzzi, and Victor L Paetznick, and Sze-Wee Tan, and John Warmington, and John H Rex, and Luis Ostrosky-Zeichner
Simple and rapid detection of Candida albicans DNA in serum by PCR for diagnosis of invasive candidiasis.
August 2000, Journal of clinical microbiology,
Copied contents to your clipboard!