Considerations for treating acne in ethnic skin. 2005

Valerie D Callender
Callender Skin & Laser Center, Mitchellville, Maryland, USA.

Patients with ethnic skin are at an increased risk for developing postinflammatory hyperpigmentation (PIH) and keloid scarring subsequent to acne lesions. Treatment approaches for acne in darker skinned patients must balance early aggressive intervention with the selection of efficacious and nonirritating agents. Most patients with prominent or long-lasting PIH will require treatment with a topical retinoid and hydroquinone, the gold standard in the treatment of PIH. Keloids may be treated with surgical excision, but the rate of recurrence can be as high as 50%. Successful management of ethnic skin with acne can be achieved with the appropriate combination drug regimen and good patient compliance. For best results, clinicians should manage the entire grooming regimen of the skin and hair of their ethnic patients.

UI MeSH Term Description Entries
D003358 Cosmetics Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995) Personal Care Products,Care Product, Personal,Care Products, Personal,Personal Care Product,Product, Personal Care,Products, Personal Care
D003998 Dicarboxylic Acids Acyclic acids that contain two carboxyl groups and have the formula HO2C-R-CO2H, where R may be an aromatic or aliphatic group. Acids, Dicarboxylic
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D006203 Hair Preparations Hair grooming, cleansing and modifying products meant for topical application to hair, usually human. They include sprays, bleaches, dyes, conditioners, rinses, shampoos, nutrient lotions, etc. Cosmetics, Hair,Hair Cosmetic,Hair Preparation,Cosmetic, Hair,Hair Cosmetics,Preparation, Hair,Preparations, Hair
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006873 Hydroquinones Derivatives of hydroquinone (1,4-dihydrobenzene) made by reduction of BENZOQUINONES. Quinol,p-Dihydroxybenzenes,para-Dihydroxybenzenes,Quinols,p Dihydroxybenzenes,para Dihydroxybenzenes
D000152 Acne Vulgaris A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors. Acne
D000153 Acne Keloid A type of acneiform disorder in which secondary pyogenic infection in and around pilosebaceous structures ends in keloidal scarring. It manifests as persistent folliculitis of the back of the neck associated with occlusion of the follicular orifices. It is most often encountered in black or Asian men. Keloidal Acne,Acne Keloidalis,Dermatitis Papillaris Capillitii,Folliculitis Keloidalis,Folliculitis Keloidalis Nuchae,Lichen Keloidalis Nuchae,Nuchal Keloid Acne,Acne Keloids,Acne, Keloidal,Acne, Nuchal Keloid,Acnes, Nuchal Keloid,Capillitii, Dermatitis Papillaris,Capillitius, Dermatitis Papillaris,Dermatitis Papillaris Capillitius,Keloid Acne, Nuchal,Keloid Acnes, Nuchal,Keloid, Acne,Keloidal Acnes,Keloidalis Nuchae, Folliculitis,Keloidalis Nuchae, Lichen,Keloids, Acne,Nuchae, Folliculitis Keloidalis,Nuchae, Lichen Keloidalis,Nuchal Keloid Acnes,Papillaris Capillitii, Dermatitis,Papillaris Capillitius, Dermatitis
D012176 Retinoids A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization. Retinoid
D017495 Hyperpigmentation Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance. Hypermelanosis,Hypermelanoses

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