BIOMAT Database Logo BIOMAT Database Logo

Photo-cross-linking interacting proteins with a genetically encoded benzophenone. 2005

Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Chemistry Department, Franklin and Marshall College, P.O. Box 3003, Lancaster, Pennsylvania 17604, USA.

UI MeSH Term Description Entries
D010649 Phenylalanine An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE. Endorphenyl,L-Phenylalanine,Phenylalanine, L-Isomer,L-Isomer Phenylalanine,Phenylalanine, L Isomer
D010777 Photochemistry A branch of physical chemistry which studies chemical reactions, isomerization and physical behavior that may occur under the influence of visible and/or ultraviolet light. Photochemistries
D010957 Plasmids Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS. Episomes,Episome,Plasmid
D003432 Cross-Linking Reagents Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. Bifunctional Reagent,Bifunctional Reagents,Cross Linking Reagent,Crosslinking Reagent,Cross Linking Reagents,Crosslinking Reagents,Linking Reagent, Cross,Linking Reagents, Cross,Reagent, Bifunctional,Reagent, Cross Linking,Reagent, Crosslinking,Reagents, Bifunctional,Reagents, Cross Linking,Reagents, Cross-Linking,Reagents, Crosslinking
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D000604 Amino Acyl-tRNA Synthetases A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS. Amino Acyl T RNA Synthetases,Amino Acyl-tRNA Ligases,Aminoacyl Transfer RNA Synthetase,Aminoacyl-tRNA Synthetase,Transfer RNA Synthetase,tRNA Synthetase,Acyl-tRNA Ligases, Amino,Acyl-tRNA Synthetases, Amino,Amino Acyl tRNA Ligases,Amino Acyl tRNA Synthetases,Aminoacyl tRNA Synthetase,Ligases, Amino Acyl-tRNA,RNA Synthetase, Transfer,Synthetase, Aminoacyl-tRNA,Synthetase, Transfer RNA,Synthetase, tRNA,Synthetases, Amino Acyl-tRNA
D001577 Benzophenones Derivatives of benzophenone (with the structural formula phenyl-(C
D013056 Spectrophotometry, Ultraviolet Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Ultraviolet Spectrophotometry
D019920 Photoaffinity Labels Biologically active molecules which are covalently bound to the enzymes or binding proteins normally acting on them. Binding occurs due to activation of the label by ultraviolet light. These labels are used primarily to identify binding sites on proteins. Labels, Photoaffinity
D025941 Protein Interaction Mapping Methods for determining interaction between PROTEINS. Interaction Mapping, Protein,Interaction Mappings, Protein,Mapping, Protein Interaction,Mappings, Protein Interaction,Protein Interaction Mappings

Related Publications

Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Protein-DNA photo-crosslinking with a genetically encoded benzophenone-containing amino acid.
September 2009, Bioorganic & medicinal chemistry letters,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Genetically Encoded 2-Aryl-5-carboxytetrazoles for Site-Selective Protein Photo-Cross-Linking.
May 2017, Journal of the American Chemical Society,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Genetically encoded cleavable protein photo-cross-linker.
August 2014, Journal of the American Chemical Society,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Genetically encoded releasable photo-cross-linking strategies for studying protein-protein interactions in living cells.
October 2017, Nature protocols,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Trapping Chromatin Interacting Proteins with Genetically Encoded, UV-Activatable Crosslinkers In Vivo.
January 2018, Methods in molecular biology (Clifton, N.J.),
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Slow photo-cross-linking kinetics of benzophenone-labeled voltage sensors of ion channels.
September 2001, Biochemistry,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Design of Light-Sensitive NMDARs by Genetically Encoded Photo-Cross-Linkers.
January 2017, Methods in molecular biology (Clifton, N.J.),
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Conditional Chaperone-Client Interactions Revealed by Genetically Encoded Photo-cross-linkers.
May 2017, Accounts of chemical research,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
HcRed, a genetically encoded fluorescent binary cross-linking agent for cross-linking of mitochondrial ATP synthase in Saccharomyces cerevisiae.
January 2012, PloS one,
Ian S Farrell, and Rebecca Toroney, and Jennifer L Hazen, and Ryan A Mehl, and Jason W Chin
Expanding the functionality of proteins with genetically encoded dibenzo[b,f][1,4,5]thiadiazepine: a photo-transducer for photo-click decoration.
March 2022, Chemical science,
Copied contents to your clipboard!