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Renal tubular acidosis (RTA) is a frequent extraglandular manifestation of Sjögren's syndrome; however, no distinction on the incidence of this renal tubular defect between primary and secondary Sjögren's syndrome has been reported. This study was undertaken in order to define the frequency of RTA and the possible pathogenetic mechanisms in a group of 21 randomly selected primary Sjögren's syndrome patients. RTA was found in 7 (33%) patients. The incomplete type of the disorder was the most frequent. It seems that the etiology of RTA is multifactorial. Renal excretion of monoclonal proteins and the immunologically-induced interstitial inflammation are the main possible factors of this renal tubular defect.
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
September 2017,
Electrolyte & blood pressure : E & BP,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
May 2015,
Rheumatology (Oxford, England),
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
July 2010,
The Journal of the Association of Physicians of India,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
April 1970,
The American journal of medicine,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
January 2018,
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
February 2006,
Rheumatology (Oxford, England),
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
April 1971,
Annals of internal medicine,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
March 1998,
Clinical nephrology,
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
January 2012,
Internal medicine (Tokyo, Japan),
K C Siamopoulos, and
M Elisaf, and
A A Drosos, and
A A Mavridis, and
H M Moutsopoulos
November 2013,
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia,
