Left-right asymmetry in the alimentary canal of the Drosophila embryo. 2005

Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
Okazaki Institute for Integrative Bioscience, National Institute for Basic Biology, National Institutes of Natural Sciences, Higashiyama, Okazaki, Aichi 444-8787, Japan.

In many animal groups, left-right (LR) asymmetry within the body is observed. The left and right sides of the body are generally defined with reference to the anterior-posterior (AP) and dorsal-ventral (DV) axes. In this study, we investigated whether LR asymmetry is solely dependent on the AP and DV polarities in Drosophila embryos. We focused on the proventriculus, a posterior part of the foregut, and the hindgut because LR asymmetry in these body parts is highly stable in normal embryos. In embryos with a fully reversed AP polarity, LR asymmetry in both the proventriculus and the hindgut was re-oriented in relation to the reversed AP polarity. This demonstrates that inversion of AP polarity does not affect LR asymmetry of these tissues, and implies that LR asymmetry is specified in relation to the AP and DV polarities. Our findings were not consistent with the alternative hypothesis that LR asymmetry is predetermined by maternal signals that localize asymmetrically along the LR axis in the oocyte and/or early embryo.

UI MeSH Term Description Entries
D008297 Male Males
D009865 Oocytes Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM). Ovocytes,Oocyte,Ovocyte
D004330 Drosophila A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology. Fruit Fly, Drosophila,Drosophila Fruit Flies,Drosophila Fruit Fly,Drosophilas,Flies, Drosophila Fruit,Fly, Drosophila Fruit,Fruit Flies, Drosophila
D004625 Embryo, Nonmammalian The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO. Embryonic Structures, Nonmammalian,Embryo, Non-Mammalian,Embryonic Structures, Non-Mammalian,Nonmammalian Embryo,Nonmammalian Embryo Structures,Nonmammalian Embryonic Structures,Embryo Structure, Nonmammalian,Embryo Structures, Nonmammalian,Embryo, Non Mammalian,Embryonic Structure, Non-Mammalian,Embryonic Structure, Nonmammalian,Embryonic Structures, Non Mammalian,Embryos, Non-Mammalian,Embryos, Nonmammalian,Non-Mammalian Embryo,Non-Mammalian Embryonic Structure,Non-Mammalian Embryonic Structures,Non-Mammalian Embryos,Nonmammalian Embryo Structure,Nonmammalian Embryonic Structure,Nonmammalian Embryos,Structure, Non-Mammalian Embryonic,Structure, Nonmammalian Embryo,Structure, Nonmammalian Embryonic,Structures, Non-Mammalian Embryonic,Structures, Nonmammalian Embryo,Structures, Nonmammalian Embryonic
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D017344 Genes, Insect The functional hereditary units of INSECTS. Insect Genes,Gene, Insect,Insect Gene
D041981 Gastrointestinal Tract Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS). Digestive Tract,GI Tract,Digestive Tracts,GI Tracts,Gastrointestinal Tracts
D019521 Body Patterning The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc. Axial Patterning (Embryology),Embryonic Pattern Formation,Polarity of Development,Body Pattern Formation,Body Pattern Specification,Embryonic Pattern Specification,Development Polarity,Embryonic Pattern Formations,Formation, Embryonic Pattern,Pattern Formation, Body,Pattern Formation, Embryonic,Pattern Specification, Body,Pattern Specification, Embryonic,Patterning, Axial (Embryology),Patterning, Body,Specification, Body Pattern,Specification, Embryonic Pattern

Related Publications

Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
June 2008, Seminars in cell & developmental biology,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
February 1998, Seminars in cell & developmental biology,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
June 2001, Development, growth & differentiation,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
December 2007, Seikagaku. The Journal of Japanese Biochemical Society,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
September 2004, Mechanisms of development,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
June 2014, Genesis (New York, N.Y. : 2000),
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
June 2015, Developmental cell,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
April 2001, Development (Cambridge, England),
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
April 2006, Nature,
Makoto Hayashi, and Hikomaru Aono, and Junichi Ishihara, and Sadaaki Oshima, and Hideaki Yamamoto, and Yu-ichi Nakazato, and Satoru Kobayashi
April 2020, PLoS genetics,
Copied contents to your clipboard!