BIOMAT Database Logo BIOMAT Database Logo

Endodermal sinus tumor of the vagina. 2007

Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Pediatric Oncology Unit, Istituto Nazionale Tumori, Milano, Italy. monica.terenziani@istitutotumori.mi.it

Malignant germ cell tumors of the vagina represent a critical site for local treatment. We report on our experience with two vaginal endodermal sinus tumors. Treatment with PEB regimen induced both tumor regression and alpha fetoprotein normalization. One patient had a residual lesion that was biopsied twice and no viable tumor cells were ever found. Both patients remained alive and disease-free, without having had surgical procedures except for biopsies. Platinum-based chemotherapy is able to achieve complete remissions and should be considered for vaginal endodermal sinus tumors.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D012074 Remission Induction Therapeutic act or process that initiates a response to a complete or partial remission level. Induction of Remission,Induction, Remission,Inductions, Remission,Remission Inductions
D001761 Bleomycin A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. BLEO-cell,Blanoxan,Blenoxane,Bleolem,Bleomicina,Bleomycin A(2),Bleomycin A2,Bleomycin B(2),Bleomycin B2,Bleomycin Sulfate,Bleomycins,Bleomycinum Mack,Bléomycine Bellon,BLEO cell,BLEOcell,Bellon, Bléomycine,Mack, Bleomycinum,Sulfate, Bleomycin
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D002945 Cisplatin An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. Platinum Diamminodichloride,cis-Diamminedichloroplatinum(II),cis-Dichlorodiammineplatinum(II),Biocisplatinum,Dichlorodiammineplatinum,NSC-119875,Platidiam,Platino,Platinol,cis-Diamminedichloroplatinum,cis-Platinum,Diamminodichloride, Platinum,cis Diamminedichloroplatinum,cis Platinum
D005047 Etoposide A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. Demethyl Epipodophyllotoxin Ethylidine Glucoside,Celltop,Eposide,Eposin,Eto-GRY,Etomedac,Etopos,Etoposide Pierre Fabre,Etoposide Teva,Etoposide, (5S)-Isomer,Etoposide, (5a alpha)-Isomer,Etoposide, (5a alpha,9 alpha)-Isomer,Etoposide, alpha-D-Glucopyranosyl Isomer,Etoposido Ferrer Farma,Exitop,Lastet,NSC-141540,Onkoposid,Riboposid,Toposar,VP 16-213,VP-16,Vepesid,Vépéside-Sandoz,Eto GRY,Etoposide, alpha D Glucopyranosyl Isomer,NSC 141540,NSC141540,Teva, Etoposide,VP 16,VP 16 213,VP 16213,VP16,Vépéside Sandoz,alpha-D-Glucopyranosyl Isomer Etoposide
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000971 Antineoplastic Combined Chemotherapy Protocols The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form. Anticancer Drug Combinations,Antineoplastic Agents, Combined,Antineoplastic Chemotherapy Protocols,Antineoplastic Drug Combinations,Cancer Chemotherapy Protocols,Chemotherapy Protocols, Antineoplastic,Drug Combinations, Antineoplastic,Antineoplastic Combined Chemotherapy Regimens,Combined Antineoplastic Agents,Agent, Combined Antineoplastic,Agents, Combined Antineoplastic,Anticancer Drug Combination,Antineoplastic Agent, Combined,Antineoplastic Chemotherapy Protocol,Antineoplastic Drug Combination,Cancer Chemotherapy Protocol,Chemotherapy Protocol, Antineoplastic,Chemotherapy Protocol, Cancer,Chemotherapy Protocols, Cancer,Combinations, Antineoplastic Drug,Combined Antineoplastic Agent,Drug Combination, Anticancer,Drug Combination, Antineoplastic,Drug Combinations, Anticancer,Protocol, Antineoplastic Chemotherapy,Protocol, Cancer Chemotherapy,Protocols, Antineoplastic Chemotherapy,Protocols, Cancer Chemotherapy
D014625 Vaginal Neoplasms Tumors or cancer of the VAGINA. Cancer of Vagina,Vaginal Cancer,Cancer of the Vagina,Neoplasms, Vaginal,Vagina Cancer,Vagina Neoplasms,Cancer, Vagina,Cancer, Vaginal,Cancers, Vagina,Cancers, Vaginal,Neoplasm, Vagina,Neoplasm, Vaginal,Neoplasms, Vagina,Vagina Cancers,Vagina Neoplasm,Vaginal Cancers,Vaginal Neoplasm

Related Publications

Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina.
December 1997, AJR. American journal of roentgenology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina.
April 2000, The Journal of urology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina.
October 1978, Gynecologic oncology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the infant vagina.
February 1985, Gynecologic oncology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of vagina in infants.
April 2013, Rare tumors,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina in children.
May 1999, Medical and pediatric oncology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina and cervix.
June 1985, Cancer,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal sinus tumor of the vagina in a child.
December 2012, Journal of obstetrics and gynaecology of India,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
Endodermal germ cell carcinoma (endodermal sinus tumor) of the vagina in infant girls.
July 1979, Journal of cancer research and clinical oncology,
Monica Terenziani, and Filippo Spreafico, and Paola Collini, and Cristina Meazza, and Maura Massimino, and Luigi Piva
[Diagnosis and treatment of endodermal sinus tumor of the vagina].
February 1999, Zhonghua fu chan ke za zhi,
Copied contents to your clipboard!