Biomaterial Database

[Shigella flexneri strains having a new type antigen]. 1992

S Matsushita, and S Yamada, and Y Kudoh

Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health.

Five Shigella strains isolated from stool cultures of two domestic dysentery cases and three imported cases in Tokyo in 1986-1989 had an atypial serotype that agglutinated with only antiserum to S. flexneri group 6 factor antigen. These strains showed typical biochemical reactions of S. flexneri and were biochemically identical. Four of the strains were positive for Serény test with guinea pig eye and the cell-invasion test with HeLa cells. The strains also had the virulence-plasmid encoding outer membrane proteins, indicating that these were pathogenic. These strains were serologically identical and gave significant cross-reactions with S. flexneri 1b and 4b that had group 6 factor antigen. However, results of reciprocal absorption tests showed that the O antigen of these strains were not identical to S. flexneri 1b and 4b, and were confirmed to have a new type antigen which can not be included among the known S. flexneri type antigen I-VI. Strain 88-893 is designated as the test strain for this new type antigen of S. flexneri.

UI	MeSH Term	Description	Entries
D004352	Drug Resistance, Microbial	The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).	Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000942	Antigens, Bacterial	Substances elaborated by bacteria that have antigenic activity.	Bacterial Antigen,Bacterial Antigens,Antigen, Bacterial
D012698	Serologic Tests	Diagnostic procedures involving immunoglobulin reactions.	Serodiagnosis,Serologic Test,Serological Tests,Test, Serologic,Tests, Serologic,Serodiagnoses,Serological Test,Test, Serological,Tests, Serological
D012763	Shigella flexneri	A bacterium which is one of the etiologic agents of bacillary dysentery (DYSENTERY, BACILLARY) and sometimes of infantile gastroenteritis.