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Positron emission tomography (PET) was performed on six patients with the Rett syndrome and the results were compared with the concurrent clinical status of the patients. The cerebral metabolic rate of oxygen (CMRO2) was low in five patients, and oxygen extraction fraction (OEF) was low in four patients; both had a tendency to decline with advancing age. Although the cause is unknown, it is suggested that impaired oxidative metabolism exists in the Rett syndrome. An analysis of the distribution among brain regions showed that the ratios of values for the frontal cortex to those for the temporal cortex for both the cerebral blood flow (CBF) and CMRO2 were lower than those for the controls, which may indicate the loss of hyperfrontality in the Rett syndrome. Distribution of brain metabolism may be immature in the Rett syndrome.
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
January 1997,
European child & adolescent psychiatry,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
February 1997,
Annals of nuclear medicine,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
June 1979,
The Journal of physiology,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
September 1982,
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
October 1985,
Seminars in nuclear medicine,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
May 1992,
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
May 1967,
The Journal of clinical investigation,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
January 1989,
The Journal of neuropsychiatry and clinical neurosciences,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
October 1988,
No to shinkei = Brain and nerve,
H Yoshikawa, and
N Fueki, and
H Suzuki, and
N Sakuragawa, and
M Iio
May 1999,
AJNR. American journal of neuroradiology,
