[Osteogenesis imperfecta--lower limb in osteogenesis imperfecta]. 2005

Jerzy Sułko
Oddział Ortopedyczno-Urazowy Katedry i Kliniki Chirurgii Pediatryicznej, Uniwersytecki Szpital Dzieciecy, Wydział Lekarski Uniwersytetu Jagiellońskiego.

The author of this paper asses lower extremity in 141 children with osteogenesis imperfecta, treated in University Children Hospital in Krakow in years 1988-2002: number of fractures, presence of the deformation, radiological findings, possibility of walking. Only 3 from this group did not suffer from lower extremity long bone fractures. In remaining patients, the number of fractures was 4 on average with type I and IV, and 46 fractures in children with type III osteogenesis imperfecta in each patient. Perinatal fractures appeared in 26 children with type II or III oi. In remaining, first fracture happened at the age of 23 months on average. 21% of the children had never walked before, and the rest of them started pionisation at the age of 20 months on average. Lower extremities deformations appeared in 113 children (80%). We assessed typical deformity pattern, based on clinical and radiological findings: varisation of femur and antecurvation of the tibia. The movement limitations in hips or knees was found in 29 children. Radiological changes in growth cartilage, so-called "popcorn calcification" were found in 15 children with type III of osteogenesis imperfecta.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D010013 Osteogenesis Imperfecta COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I. Fragilitas Ossium,Lobstein Disease,Brittle Bone Disease,Lobstein's Disease,Osteogenesis Imperfecta Tarda,Osteogenesis Imperfecta with Blue Sclerae,Osteogenesis Imperfecta, Type 1,Osteogenesis Imperfecta, Type I,Disease, Lobstein,Disease, Lobstein's,Lobsteins Disease,Ossiums, Fragilitas,Osteogenesis Imperfecta Tardas
D011859 Radiography Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film). Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D035002 Lower Extremity The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG. Extremity, Lower,Lower Limb,Membrum inferius,Extremities, Lower,Limb, Lower,Limbs, Lower,Lower Extremities,Lower Limbs
D038061 Lower Extremity Deformities, Congenital Congenital structural abnormalities of the LOWER EXTREMITY. Lower Limb Deformities, Congenital

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