Biomaterial Database

[Acupuncture for treatment of simple obesity and its effect on serum leptin level of the patient]. 2005

Suo-bin Kang, and Xiu-ling Gao, and Shao-jin Wang, and Yan-jun Wang

TCM Hospital of Hebei Medical University, Shijiazhuang, China.

OBJECTIVE To explore the therapeutic effect and the mechanism of acupuncture in reducing body weight. METHODS Fifty cases of simple obesity were randomly divided into an acupuncture group and a drug control group, 25 cases in each group. The patients in the acupuncture group were treated with body acupuncture at Tianshu (ST 25), Guanyuan (CV 4), etc, electroacupuncture and ear point tapping and pressing therapy (Shenmen, Endocrine, etc. were selected); the patients in the control group were treated with oral administration of sibutramine. The serum leptin level before and after treatment were determined and the therapeutic effect in reducing body weight was assessed. RESULTS The total effective rate was 88.0% in the acupuncture group and 80. 0% in the control group, with no significant difference between the two groups (P>0.05); after treatment, the serum leptin level in both the two groups decreased significantly (P<0.01), and the decreasing amplitude in the acupuncture group was superior to that in the control group (P<0.05). CONCLUSIONS Acupuncture therapy has a definite therapeutic effect in reducing body weight, and the improvement of serum leptin level of the patient is possibly one of the mechanisms of acupuncture in reducing body weight.

UI	MeSH Term	Description	Entries
D009765	Obesity	A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015669	Acupuncture Points	Designated locations along nerves or organ meridians for inserting acupuncture needles.	Acupoints,Acupoint,Acupuncture Point,Point, Acupuncture,Points, Acupuncture
D015670	Acupuncture Therapy	Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. It is sometimes used in conjunction with heat, moxibustion, acupressure, or electric stimulation.	Acupotomy,Acupuncture Treatment,Pharmacoacupuncture Therapy,Pharmacoacupuncture Treatment,Therapy, Acupuncture,Acupotomies,Acupuncture Treatments,Therapy, Pharmacoacupuncture,Treatment, Acupuncture,Treatment, Pharmacoacupuncture
D015671	Electroacupuncture	A form of acupuncture with electrical impulses passing through the needles to stimulate NERVE TISSUE. It can be used for ANALGESIA; ANESTHESIA; REHABILITATION; and treatment for diseases.
D020738	Leptin	A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.	Ob Protein,Obese Protein,Ob Gene Product,Obese Gene Product,Gene Product, Ob,Gene Product, Obese